Semen retrieval and analysis in men with myelomeningocele

被引:15
作者
Hultling, C [1 ]
Levi, R
Amark, P
Sjöblom, P
机构
[1] Karolinska Hosp, Spinalis SCI Res Unit, S-17176 Stockholm, Sweden
[2] Karolinska Hosp, Astrid Lindgren Childrens Hosp, Neuropediat Sect, S-17176 Stockholm, Sweden
[3] Huddinge Univ Hosp, Karolinska Inst, Dept Obstet & Gynaecol, S-14186 Huddinge, Sweden
关键词
D O I
10.1017/S0012162200001250
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The introduction of advanced assisted reproduction technologies (ART) has created opportunities for the treatment of infertility among patients with myelomeningocele (MMC). The aim of this study was to assess the possibility of semen retrieval and to analyse the semen quality in men with MMC. Nine men, aged 22 to 39 with MMC participated in the study. Two participants were able to achieve unassisted ejaculation. Vibratory stimulation was unsuccessfully attempted in the remaining seven participants who then underwent electroejaculation under general anaesthesia. In total, enough spermatozoa for intracytoplasmic spermatozoa injection were retrieved from five participants. In four cases, no spermatozoa were observed in the ejaculates. Testicular biopsies, however, revealed spermatogenesis, and thus a reproductive potential, in one of these men. Therefore, in six of the nine men with MMC, fatherhood seemed possible with modern ART, despite the semen quality generally being very poor.
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页码:681 / 684
页数:4
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