Combination of scanning probe technology with photonic nanojets

被引:66
作者
Duocastella, Marti [1 ]
Tantussi, Francesco [1 ]
Haddadpour, Ali [2 ,3 ]
Zaccaria, Remo Proietti [1 ]
Jacassi, Andrea [1 ]
Veronis, Georgios [2 ,3 ]
Diaspro, Alberto [1 ]
De Angelis, Francesco [1 ]
机构
[1] Ist Italiano Tecnol, Nanophys, Via Morego 30, I-16063 Genoa, Italy
[2] Louisiana State Univ, Sch Elect Engn & Comp Sci, Baton Rouge, LA 70803 USA
[3] Louisiana State Univ, Ctr Computat & Technol, Baton Rouge, LA 70803 USA
来源
SCIENTIFIC REPORTS | 2017年 / 7卷
基金
美国国家科学基金会; 欧洲研究理事会;
关键词
MOVABLE THIN-FILMS; SUPERRESOLUTION MICROSCOPY; RESOLUTION; MICROSPHERES;
D O I
10.1038/s41598-017-03726-5
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Light focusing through a microbead leads to the formation of a photonic nanojet functional for enhancing the spatial resolution of traditional optical systems. Despite numerous works that prove this phenomenon, a method to appropriately translate the nanojet on top of a region of interest is still missing. Here, by using advanced 3D fabrication techniques we integrated a microbead on an AFM cantilever thus realizing a system to efficiently position nanojets. This fabrication approach is robust and can be exploited in a myriad of applications, ranging from microscopy to Raman spectroscopy. We demonstrate the potential of portable nanojets by imaging different sub-wavelength structures. Thanks to the achieved portability, we were able to perform a detailed optical characterization of the resolution enhancement induced by the microbead, which sheds light into the many contradictory resolution claims present in literature. Our conclusions are strongly supported by rigorous data analysis and by numerical simulations, all in perfect agreement with experimental results.
引用
收藏
页数:7
相关论文
共 42 条
  • [1] Super-resolution microscopy by movable thin-films with embedded microspheres: Resolution analysis
    Allen, Kenneth W.
    Farahi, Navid
    Li, Yangcheng
    Limberopoulos, Nicholaos I.
    Walker, Dennis E., Jr.
    Urbas, Augustine M.
    Liberman, Vladimir
    Astratov, Vasily N.
    [J]. ANNALEN DER PHYSIK, 2015, 527 (7-8) : 513 - 522
  • [2] Angelis F. D., 2011, NATURE PHOTON, V5, P2
  • [3] SINGLE MOLECULES OBSERVED BY NEAR-FIELD SCANNING OPTICAL MICROSCOPY
    BETZIG, E
    CHICHESTER, RJ
    [J]. SCIENCE, 1993, 262 (5138) : 1422 - 1425
  • [4] Imaging intracellular fluorescent proteins at nanometer resolution
    Betzig, Eric
    Patterson, George H.
    Sougrat, Rachid
    Lindwasser, O. Wolf
    Olenych, Scott
    Bonifacino, Juan S.
    Davidson, Michael W.
    Lippincott-Schwartz, Jennifer
    Hess, Harald F.
    [J]. SCIENCE, 2006, 313 (5793) : 1642 - 1645
  • [5] Comment on 'Super-resolution microscopy by movable thin-films with embedded microspheres: Resolution analysis' [Ann. Phys. (Berlin) 527, 513 (2015)]
    Darafsheh, Arash
    [J]. ANNALEN DER PHYSIK, 2016, 528 (11-12) : 898 - 900
  • [6] Biological super-resolution imaging by using novel microsphere-embedded coverslips
    Darafsheh, Arash
    Guardiola, Consuelo
    Nihalani, Deepak
    Lee, Daeyeon
    Finlay, Jarod C.
    Carabe, Alejandro
    [J]. NANOSCALE IMAGING, SENSING, AND ACTUATION FOR BIOMEDICAL APPLICATIONS XII, 2015, 9337
  • [7] Optical super-resolution imaging by high-index microspheres embedded in elastomers
    Darafsheh, Arash
    Guardiola, Consuelo
    Palovcak, Averie
    Finlay, Jarod C.
    Carabe, Alejandro
    [J]. OPTICS LETTERS, 2015, 40 (01) : 5 - 8
  • [8] Advantages of microsphere-assisted super-resolution imaging technique over solid immersion lens and confocal microscopies
    Darafsheh, Arash
    Limberopoulos, Nicholaos I.
    Derov, John S.
    Walker, Dennis E., Jr.
    Astratov, Vasily N.
    [J]. APPLIED PHYSICS LETTERS, 2014, 104 (06)
  • [9] Optical super-resolution by high-index liquid-immersed microspheres
    Darafsheh, Arash
    Walsh, Gary F.
    Dal Negro, Luca
    Astratov, Vasily N.
    [J]. APPLIED PHYSICS LETTERS, 2012, 101 (14)
  • [10] Darafsheh Arash., 2013, OPTICAL SUPER RESOLU