Angiotensin-(1-7): An active member of the renin-angiotensin system

被引：0
作者：
Kucharewicz, I [1 ]
Pawlak, R [1 ]
Matys, T [1 ]
Chabielska, E [1 ]
Buczko, W [1 ]
机构：
[1] Med Acad Bialystok, Dept Pharmacodynam, PL-15230 Bialystok, Poland
来源：
JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | 2002年 / 53卷 / 04期
关键词：
angiotensin-(1-7); renin-angiotensin system; angiotensin receptors;
D O I：
暂无
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Angiotensin-(1-7) [An-(1-7)] is an active member of renin-angiotensin system (RAS). It counterbalances vasoconstriction, mitogenic, arrhythmogenic and oprothrombotic actions of Ang II. Inducing natiuresis and diuresis opposes also the water and sodium retention produced by Ang II. Till now the specific receptor side for Ang-(1-7) has been not cloned, but the current data Strongly suggest that an interaction (cross- talk) between angiotensin receptors may play a role in the effects of Ang-(1-7).
引用
收藏
页码：533 / 540
页数：8
相关论文
共 60 条
[1]   Angiotensin-(1-7) induces bradykinin-mediated hypotensive responses in anesthetized rats [J].
Abbas, A ;
Gorelik, G ;
Carbini, LA ;
Scicli, AG .
HYPERTENSION, 1997, 30 (02) :217-221
[2]   Pathways for angiotensin-(1-7) metabolism in pulmonary and renal tissues [J].
Allred, AJ ;
Diz, DI ;
Ferrario, CM ;
Chappell, MC .
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2000, 279 (05) :F841-F850
[3]   [7-D-ALA]-ANGIOTENSIN-(1-7) - SELECTIVE ANTAGONISM OF ANGIOTENSIN-(1-7) IN THE RAT PARAVENTRICULAR NUCLEUS [J].
AMBUHL, P ;
FELIX, D ;
KHOSLA, MC .
BRAIN RESEARCH BULLETIN, 1994, 35 (04) :289-291
[4]  
Aurell Mattias, 1998, Blood Pressure, V7, P71, DOI 10.1080/080370598437420
[5]   ANTIHYPERTENSIVE ACTIONS OF ANGIOTENSIN-(1-7) IN SPONTANEOUSLY HYPERTENSIVE RATS [J].
BENTER, IF ;
FERRARIO, CM ;
MORRIS, M ;
DIZ, DI .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 1995, 269 (01) :H313-H319
[6]  
Brosnihan KB, 1998, AM J CARDIOL, V82, p17S, DOI 10.1016/S0002-9149(98)90425-8
[7]   Angiotensin-(1-7) dilates canine coronary arteries through kinins and nitric oxide [J].
Brosnihan, KB ;
Li, P ;
Ferrario, CM .
HYPERTENSION, 1996, 27 (03) :523-528
[8]  
Brosnihan KB, 1998, BIOL RES, V31, P227
[9]  
Burnett J C Jr, 1999, J Hypertens Suppl, V17, pS37
[10]   RETENTION OF CEREBROVASCULAR DILATION AFTER CORTICAL SPREADING DEPRESSION IN ANESTHETIZED RABBITS [J].
BUSIJA, DW ;
MENG, W .
STROKE, 1993, 24 (11) :1740-1745
123456