An efficient approach for the synthesis of spirooxindole derivatives catalyzed by novel sulfated choline based heteropolyanion at room temperature

被引:54
|
作者
Satasia, Shailesh P. [1 ]
Kalaria, Piyush N. [1 ]
Avalani, Jemin R. [1 ]
Raval, Dipak K. [1 ]
机构
[1] Sardar Patel Univ, Dept Chem, Vallabh Vidyanagar 388120, Gujarat, India
关键词
Spirooxindoles; Heterogeneous catalyst; Green procedure; Multi-component reactions; ONE-POT SYNTHESIS; ACIDIC IONIC LIQUID; CELLULOSE;
D O I
10.1016/j.tet.2014.06.050
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new zwitterionic salt, sulfated choline based heteropolyanion, which was reported earlier by our group, has been found to be very effective for the synthesis of spirooxindole derivatives at room temperature. The heteropolyanion based on sulfated ionic liquid (HIL) showed promising features for the reaction, such as shorter reaction time, high product yields (about 90-95%), simple work up, easy removal, and reusability of the catalyst for several times without significant loss in its efficiency. This has made the protocol sustainable and economic. (C) 2014 Elsevier Ltd. All rights reserved.
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收藏
页码:5763 / 5767
页数:5
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