Pathogenesis of Retraction Pocket of the Tympanic Membrane-A Narrative Review

被引：10
作者：
Urik, Milan [1 ]
Tedla, Miroslav [2 ]
Hurnik, Pavel [3 ,4 ]
机构：
[1] Masaryk Univ Brno, Univ Hosp Brno, Fac Med, Dept Paediat Otorhinolaryngol, Brno 61300, Czech Republic
[2] Comenius Univ, Univ Hosp, Dept Otorhinolaryngol Head & Neck Surg, Bratislava 85107, Slovakia
[3] Univ Hosp Ostrava, Inst Pathol, Ostrava 70852, Czech Republic
[4] Czech Acad Sci, Inst Anim Physiol & Genet, Brno 60200, Czech Republic
来源：
MEDICINA-LITHUANIA | 2021年 / 57卷 / 05期
关键词：
retraction pocket; tympanic membrane; pathogenesis; pathology; chronic otitis media; cholesteatoma; PARS TENSA; SECRETORY OTITIS; EUSTACHIAN-TUBE; MIDDLE-EAR; CHOLESTEATOMA; VENTILATION; ANATOMY; PATHOLOGY; CHILDREN;
D O I：
10.3390/medicina57050425
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Several theories describe the development of the retraction pocket of the tympanic membrane (RP). Many authors suggest that the negative middle ear pressure is the main reason responsible for developing this condition. A narrative review has been undertaken, and conclusions are drawn reflecting a current knowledge with our new observations in the histological and immunohistochemical study. Recent studies show the important role of inflammation in the development and progression of RP. A review of the available literature shows that the inflammation plays a key role in pathogenesis of the RP and its progression to the cholesteatoma. We support this statement with our new results from histological and immunohistochemical analysis of the RPs.
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页数：7
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