Arthritis Gene Therapy Trials Reach Phase II

被引：11

作者：

Evans, Christopher ^{[1
]}

机构：

[1] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Boston, MA 02215 USA

来源：

JOURNAL OF RHEUMATOLOGY | 2010年 / 37卷 / 04期

关键词：

LEBERS CONGENITAL AMAUROSIS; ADENOASSOCIATED VIRUS; VECTOR; JOINTS; RESPONSES; DELIVERY; SAFETY; AAV;

D O I：

10.3899/jrheum.100055

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：683 / 685

页数：3

共 22 条

[1] Adeno-associated virus pseudotype 5 vector improves gene transfer in arthritic joints [J].

Apparailly, F ;

Khoury, M ;

Vervoordeldonk, MJB ;

Adriaansen, J ;

Gicquel, E ;

Perez, N ;

Riviere, C ;

Louis-Plence, P ;

Noel, D ;

Danos, O ;

Douar, AM ;

Tak, PP ;

Jorgensen, C .

HUMAN GENE THERAPY, 2005, 16 (04) :426-434

[2] Effect of gene therapy on visual function in Leber's congenital amaurosis [J].

Bainbridge, James W. B. ;

Smith, Alexander J. ;

Barker, Susie S. ;

Robbie, Scott ;

Henderson, Robert ;

Balaggan, Kamaljit ;

Viswanathan, Ananth ;

Holder, Graham E. ;

Stockman, Andrew ;

Tyler, Nick ;

Petersen-Jones, Simon ;

Bhattacharya, Shomi S. ;

Thrasher, Adrian J. ;

Fitzke, Fred W. ;

Carter, Barrie J. ;

Rubin, Gary S. ;

Moore, Anthony T. ;

Ali, Robin R. .

NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (21) :2231-2239

[3] GENE-TRANSFER TO SYNOVIOCYTES - PROSPECTS FOR GENE TREATMENT OF ARTHRITIS [J].

BANDARA, G ;

ROBBINS, PD ;

GEORGESCU, HI ;

MUELLER, GM ;

GLORIOSO, JC ;

EVANS, CH .

DNA AND CELL BIOLOGY, 1992, 11 (03) :227-231

[4] Synoviocyte infection with adeno-associated virus (AAV) is neutralized by human synovial fluid from arthritis patients and depends on AAV serotype [J].

Boissier, M.-C. ;

Lemeiter, D. ;

Clavel, C. ;

Valvason, C. ;

Laroche, L. ;

Begue, T. ;

Bessis, N. .

HUMAN GENE THERAPY, 2007, 18 (06) :525-535

[5] Intraarticular gene transfer of TNFR:Fc suppresses experimental arthritis with reduced systemic distribution of the gene product [J].

Chan, JMK ;

Villarreal, G ;

Jin, WW ;

Stepan, T ;

Burstein, H ;

Wahl, SM .

MOLECULAR THERAPY, 2002, 6 (06) :727-736

[6] Gene transfer to human joints: Progress toward a gene therapy of arthritis [J].

Evans, CH ;

Robbins, PD ;

Ghivizzani, SC ;

Wasko, MC ;

Tomaino, MM ;

Kang, R ;

Muzzonigro, TA ;

Vogt, M ;

Elder, EM ;

Whiteside, TL ;

Watkins, SC ;

Herndon, JH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (24) :8698-8703

[7]

EVANS CH, 2008, FUTURE RHEUMATOL, V3, P207

[8] Arthritis gene therapy's first death [J].

Evans, Christopher H. ;

Ghivizzani, Steven C. ;

Robbins, Paul D. .

ARTHRITIS RESEARCH & THERAPY, 2008, 10 (03)

[9] Gene therapy for arthritis - What next? [J].

Evans, Christopher H. ;

Ghivizzani, Steven C. ;

Robbins, Paul D. .

ARTHRITIS AND RHEUMATISM, 2006, 54 (06) :1714-1729

[10] Gene therapy of the rheumatic diseases: 1998 to 2008 [J].

Evans, Christopher H. ;

Ghivizzani, Steven C. ;

Robbins, Paul D. .

ARTHRITIS RESEARCH & THERAPY, 2009, 11 (01)

← 1 2 3 →