Sensory coding of pheromone signals in mammals

被引：96
作者：
Dulac, C [1 ]
机构：
[1] Harvard Univ, Howard Hughes Med Inst, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA
来源：
CURRENT OPINION IN NEUROBIOLOGY | 2000年 / 10卷 / 04期
关键词：
D O I：
10.1016/S0959-4388(00)00121-5
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The vomeronasal organ (VNO) of mammals plays an essential role in the detection of pheromones, chemical cues secreted by animals that elicit genetically programmed sexual and aggressive behaviors among conspecifics. The recent characterization of genes encoding molecular components of the VNO sensory response suggests that VNO neurons express a unique set of molecules to recognize and translate pheromone signals into neuronal electrical activity. Identification of these genes, which include putative pheromone receptor genes, has offered a new opportunity to uncover basic principles of pheromone sensory processing and important aspects of vomeronasal development.
引用
收藏
页码：511 / 518
页数：8
相关论文
共 60 条
[31]  
LUO YQ, 1994, J BIOL CHEM, V269, P16867
[32]   Differential projections from the anterior and posterior divisions of the accessory olfactory bulb to the medial amygdala in the opossum, Monodelphis domestica [J].
Martínez-Marcos, A ;
Halpern, M .
EUROPEAN JOURNAL OF NEUROSCIENCE, 1999, 11 (11) :3789-3799
[33]   A family of candidate taste receptors in human and mouse [J].
Matsunami, H ;
Montmayeur, JP ;
Buck, LB .
NATURE, 2000, 404 (6778) :601-+
[34]   A multigene family encoding a diverse array of putative pheromone receptors in mammals [J].
Matsunami, H ;
Buck, LB .
CELL, 1997, 90 (04) :775-784
[35]   Specific expression pattern of Fos in the accessory olfactory bulb of male mice after exposure to soiled bedding of females [J].
Matsuoka, M ;
Yokosuka, M ;
Mori, Y ;
Ichikawa, M .
NEUROSCIENCE RESEARCH, 1999, 35 (03) :189-195
[36]   Visualizing an olfactory sensory map [J].
Mombaerts, P ;
Wang, F ;
Dulac, C ;
Chao, SK ;
Nemes, A ;
Mendelsohn, M ;
Edmondson, J ;
Axel, R .
CELL, 1996, 87 (04) :675-686
[37]   Putative pheromone receptors related to the Ca2+-sensing receptor in Fugu [J].
Naito, T ;
Saito, Y ;
Yamamoto, J ;
Nozaki, Y ;
Tomura, K ;
Hazama, M ;
Nakanishi, S ;
Brenner, S .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (09) :5178-5181
[38]   SYNTHETIC PHEROMONES THAT PROMOTE INTER-MALE AGGRESSION IN MICE [J].
NOVOTNY, M ;
HARVEY, S ;
JEMIOLO, B ;
ALBERTS, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (07) :2059-2061
[39]   A unique urinary constituent, 6-hydroxy-6-methyl-3-heptanone, is a pheromone that accelerates puberty in female mice [J].
Novotny, MV ;
Jemiolo, B ;
Wiesler, D ;
Ma, WD ;
Harvey, S ;
Xu, FQ ;
Xie, TM ;
Carmack, M .
CHEMISTRY & BIOLOGY, 1999, 6 (06) :377-383
[40]   Positive identification of the puberty-accelerating pheromone of the house mouse:: the volatile ligands associating with the major urinary protein [J].
Novotny, MV ;
Ma, WD ;
Wiesler, D ;
Zídek, L .
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1999, 266 (1432) :2017-2022
123456