Vertebral Osteomyelitis.

被引:383
作者
Zimmerli, Werner [1 ]
机构
[1] Univ Basel, Med Clin, Kantonsspital, Liestal, Switzerland
关键词
STAPHYLOCOCCUS-AUREUS; SPINAL OSTEOMYELITIS; FOLLOW-UP; INFECTIONS; DIAGNOSIS; SPONDYLODISCITIS; VANCOMYCIN; MANAGEMENT; DISCITIS; RIFAMPIN;
D O I
10.1056/NEJMcp0910753
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 57-year-old man presents with fever, chills, and new lumbar back pain 2 weeks after undergoing a prostate biopsy because of an increased prostate-specific antigen level. His temperature is 39.7 degrees C; he has an enlarged, tender prostate and lumbar spine tenderness. His white-cell count is 9100 per cubic millimeter, and the C-reactive protein level is 343 mg per liter. Urine and blood cultures reveal multidrug-resistant, extended-spectrum beta-lactamase-producing Escherichia coli susceptible to imipenem. How should he be evaluated and treated?
引用
收藏
页码:1022 / 1029
页数:8
相关论文
共 46 条
  • [1] Spinal infections - Diagnostic tests and imaging studies
    An, Howard S.
    Seldomridge, J. Alex
    [J]. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2006, (444) : 27 - 33
  • [2] [Anonymous], SPERRYVILLE ANTIMICR
  • [3] BATEMAN JL, 1995, ORTHOPEDICS, V18, P561
  • [4] Spondylodiscitis associated with bacteraemia due to coagulase-negative staphylococci
    Bucher, E
    Trampuz, A
    Donati, L
    Zimmerli, W
    [J]. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2000, 19 (02) : 118 - 120
  • [5] Does acute placement of instrumentation in the treatment of vertebral osteomyelitis predispose to recurrent infection - Long-term follow-up in immune-suppressed patients
    Carragee, Eugene
    Iezza, Alexander
    [J]. SPINE, 2008, 33 (19) : 2089 - 2093
  • [6] Champsaur P, 2000, J RADIOL, V81, P516
  • [7] Pyogenic, tuberculous, and brucellar vertebral osteomyelitis:: a descriptive and comparative study of 219 cases
    Colmenero, JD
    Jiménez-Mejías, ME
    Sánchez-Lora, FJ
    Reguera, JM
    Palomino-Nicás, J
    Martos, F
    Heras, JGD
    Pachón, J
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 1997, 56 (12) : 709 - 715
  • [8] Coskun-Ari FF, 2008, EUR J MED RES, V13, P366
  • [9] Safety and Efficacy of Daptomycin in the Treatment of Osteomyelitis: Results from the CORE® Registry
    Crompton, J. A.
    North, D. S.
    McConnell, S. A.
    Lamp, K. C.
    [J]. JOURNAL OF CHEMOTHERAPY, 2009, 21 (04) : 414 - 420
  • [10] Usefulness of broad-range PCR for the diagnosis of osteoarticular infections
    Fenollar, Florence
    Levy, Pierre-Yves
    Raoult, Didier
    [J]. CURRENT OPINION IN RHEUMATOLOGY, 2008, 20 (04) : 463 - 470