Axon growth inhibition: signals from the p75 neurotrophin receptor

被引：29
|
作者：
Kaplan, DR [1 ]
Miller, FD [1 ]
机构：
[1] Univ Toronto, Hosp Sick Children, Dept Mol & Med Genet, Toronto, ON M5G 1X8, Canada
来源：
NATURE NEUROSCIENCE | 2003年 / 6卷 / 05期
关键词：
D O I：
10.1038/nn0503-435
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Axon growth after CNS injury is restricted in part by several inhibitors found in myelin. The Inhibition requires Interaction of the Nogo receptor with the p75 neurotrophin receptor. A new paper now shows that the Rho inhibitor Rho-GDIalpha mediates this signaling.
引用
收藏
页码：435 / 436
页数：2
相关论文
共 50 条
  • [31] The neurotrophin receptor p75 regulates gustatory axon branching and promotes innervation of the tongue during development
    Da Fei
    Tao Huang
    Robin F Krimm
    Neural Development, 9
  • [32] Modulation of Semaphorin3A activity by p75 neurotrophin receptor influences peripheral axon Patterning
    Ben-Zvi, Ayal
    Ben-Gigi, Liat
    Klein, Hagit
    Behar, Oded
    JOURNAL OF NEUROSCIENCE, 2007, 27 (47): : 13000 - 13011
  • [33] A comparison of the cytoplasmic domains of the Fas receptor and the p75 neurotrophin receptor
    H Kong
    AH Kim
    JR Orlinick
    MV Chao
    Cell Death & Differentiation, 1999, 6 : 1133 - 1142
  • [34] A comparison of the cytoplasmic domains of the Fas receptor and the p75 neurotrophin receptor
    Kong, H
    Kim, AH
    Orlinick, JR
    Chao, MV
    CELL DEATH AND DIFFERENTIATION, 1999, 6 (11): : 1133 - 1142
  • [35] Control of the cell cycle by neurotrophins:: lessons from the p75 neurotrophin receptor
    López-Sánchez, N
    Frade, JM
    HISTOLOGY AND HISTOPATHOLOGY, 2002, 17 (04) : 1227 - 1237
  • [36] Nerve Growth Factor Attenuates Proliferation of Astrocytes via the p75 Neurotrophin Receptor
    Cragnolini, Andrea B.
    Huang, Yangyang
    Gokina, Pradeepa
    Friedman, Wilma J.
    GLIA, 2009, 57 (13) : 1386 - 1392
  • [37] The p75 neurotrophin receptor: multiple interactors and numerous functions
    Gentry, JJ
    Barker, PA
    Carter, BD
    NGF AND RELATED MOLECULES IN HEALTH AND DISEASE, 2004, 146 : 25 - 39
  • [38] Neurotrophin receptor p75 regulates the invasiveness of malignant gliomas
    Nature Clinical Practice Neurology, 2007, 3 (11): : 597 - 597
  • [39] p75 Neurotrophin receptor is required for glioma invasion and proliferation
    Kenchappa, Rajappa S.
    Valadez, J. Gerardo
    Carter, Bruce D.
    Cooper, Michael K.
    Forsyth, Peter A.
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2012, 30 : S17 - S17
  • [40] Small Molecule Modulation of p75 Neurotrophin Receptor Functions
    Longo, Frank M.
    Massa, Stephen M.
    CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 2008, 7 (01) : 63 - 70
12345