Axon growth inhibition: signals from the p75 neurotrophin receptor

被引:29
|
作者
Kaplan, DR [1 ]
Miller, FD [1 ]
机构
[1] Univ Toronto, Hosp Sick Children, Dept Mol & Med Genet, Toronto, ON M5G 1X8, Canada
关键词
D O I
10.1038/nn0503-435
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Axon growth after CNS injury is restricted in part by several inhibitors found in myelin. The Inhibition requires Interaction of the Nogo receptor with the p75 neurotrophin receptor. A new paper now shows that the Rho inhibitor Rho-GDIalpha mediates this signaling.
引用
收藏
页码:435 / 436
页数:2
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