Exposure to extremely low-frequency magnetic field affects biofilm formation by cystic fibrosis pathogens

被引：9

作者：

Di Bonaventura, Giovanni ^{[1
,2
]}

Pompilio, Arianna ^{[1
,2
]}

Crocetta, Valentina ^{[1
,2
]}

De Nicola, Serena ^{[1
,2
]}

Barbaro, Filippo ^{[3
,4
]}

Giuliani, Livio ^{[5
]}

D'Emilia, Enrico ^{[5
]}

Fiscarelli, Ersilia ^{[6
]}

Bellomo, Rosa Grazia ^{[7
]}

Saggini, Raoul ^{[4
]}

机构：

[1] G dAnnunzio Univ Chieti Pescara, Dept Expt & Clin Sci, Chieti, Italy

[2] Univ G dAnnunzio, Ctr Excellence Ageing, Chieti, Italy

[3] Prometeo Srl, Padua, Italy

[4] G dAnnunzio Univ Chieti Pescara, Dept Neurosci & Imaging, Chieti, Italy

[5] Res Ctr Monteporzio Catone, INAIL, Workers Compensat Author, Rome, Italy

[6] Bambino Gesu Childrens Hosp & Res Inst, Rome, Italy

[7] G dAnnunzio Univ Chieti Pescara, Dept Med & Ageing Sci, Chieti, Italy

来源：

FUTURE MICROBIOLOGY | 2014年 / 9卷 / 12期

关键词：

biofilm formation; Burkholderia cepacia; cystic fibrosis; extremely low-frequency magnetic field; lung infection; Pseudomonas aeruginosa; Staphylococcus aureus; Stenotrophomonas maltophilia; RESISTANT STAPHYLOCOCCUS-AUREUS; MICROBIAL-GROWTH INHIBITION; CELL-GROWTH; ADHESION; AUGMENTATION; RESONANCE; MICE;

D O I：

10.2217/fmb.14.96

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Aims: To evaluate the in vitro effects of extremely low-frequency magnetic field (ELF-MF) on growth and biofilm formation by Staphylococcus aureus, Pseudomonas aeruginosa, Burkholderia cepacia and Stenotrophomonas maltophilia strains from cystic fibrosis patients. Materials & methods: The motion of selected ions (Fe, Ca, Cu, Zn, Mg, K, Na) was stimulated by the ion resonance effect, then influence on growth and biofilm formation/viability was assessed by spectrophotometry or viability count. Results: Generally, exposure to ELF-MF significantly increased bacterial growth and affected both biofilm formation and viability, although with differences with regard to ions and species considered. Conclusion: Exposure to ELF-MF represents a possible new approach for treatment of biofilm-associated cystic fibrosis lung infections.

引用

页码：1303 / 1317

页数：15

共 57 条

[1]

[Anonymous], COCHRANE DATABASE SY

[2]

Bayr E, 2013, ELECTROMAGN BIOL MED

[3]

Benson D E, 1994, ASAIO J, V40, pM371, DOI 10.1097/00002480-199407000-00025

[4] Microbial contamination of nebulizers in the home treatment of cystic fibrosis [J].