Transcranial Magnetic Stimulation for Drug-Resistant Epilepsies: Rationale and Clinical Experience

被引：47

作者：

Kimiskidis, Vasilios K. ^{[1
]}

机构：

[1] Aristotle Univ Thessaloniki, Dept Neurol 3, GR-57010 Thessaloniki, Greece

来源：

EUROPEAN NEUROLOGY | 2010年 / 63卷 / 04期

关键词：

Drug-resistant epilepsies; Epilepsy; Repetitive transcranial magnetic stimulation; Transcranial magnetic stimulation; CORTICAL DYSPLASIA; REPETITIVE TMS; SUSCEPTIBILITY; RESPONSES; SEIZURES; TRIAL; RATS; RTMS; EEG;

D O I：

10.1159/000282735

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique which, over the last 25 years, has greatly expanded from a simple method for stimulating the motor cortex to an invaluable tool with multiple research, diagnostic and even therapeutic applications. In this review, we discuss the use of repetitive TMS as a means of suppressing cortical hyperexcitability in drug-resistant epilepsies. The theoretical background and the experimental evidence in favor of this novel therapeutic approach are presented, and a number of open-label and controlled studies in patients with various forms of focal epilepsy are reviewed. It is concluded that, although the therapeutic effects of repetitive TMS in epilepsy appear rather limited, further clinical testing of this rapidly evolving technology is warranted. Copyright (C) 2010 S. Karger AG, Basel

引用

页码：205 / 210

页数：6

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