NADPH diaphorase reactive neurons in temporal lobe cortex of patients with intractable epilepsy and hippocampal sclerosis

被引：6

作者：

D'Alessio, Luciana ^{[1
]}

Lopez-Costa, Juan Jose ^{[1
]}

Konopka, Hector ^{[1
]}

Consalvo, Damian ^{[1
]}

Seoane, Eduardo ^{[1
]}

Lopez, Maria Esther ^{[1
]}

Guelman, Maria Laura ^{[1
]}

Kochen, Silvia ^{[1
]}

Zieher, Luis Maria ^{[1
]}

机构：

[1] Univ Buenos Aires, Inst Mol Biol, Ramos Mejia Hosp, Epilepsy Ctr, RA-1201 Buenos Aires, Buenos Aires, Argentina

来源：

EPILEPSY RESEARCH | 2007年 / 74卷 / 2-3期

关键词：

nitric oxide; NADPH-diaphorase; temporal lobe epilepsy; hippocampal; sclerosis; temporal cortex;

D O I：

10.1016/j.eplepsyres.2007.02.007

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Several studies have demonstrated a controversial involvement of NO in epileptogenesis. The aim of this study is to compare the NADPH diaphorase (NADPH-d) reactivity in the temporal cortex between surgical specimens of patients with intractable epilepsy and hippocampal sclerosis and autopsy controls. Brain samples of patients and postmortem controls were stained with the NADPH-d technique. Sprouting and larger areas of NADPH-d reactive neurons were found in the temporal cortex of epileptic patients. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：228 / 231

页数：4

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