Enantioselective construction of lactone[2,3-b]piperidine skeletons via organocatalytic tandem reactions

被引：37
|
作者：
He, Zhao-Quan [1 ,2 ]
Han, Bo [2 ]
Li, Rui [1 ]
Wu, Li [2 ]
Chen, Ying-Chun [1 ,2 ]
机构：
[1] Sichuan Univ, State Key Lab Biotherapy, W China Hosp, Chengdu 610041, Peoples R China
[2] Sichuan Univ, Key Lab Drug Targeting & Drug Delivery Syst, Dept Med Chem, W China Sch Pharm,Educ Minist, Chengdu 610041, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2010年 / 8卷 / 04期
基金：
中国国家自然科学基金;
关键词：
DIELS-ALDER REACTION; IODOXYBENZOIC ACID IBX; ALPHA; BETA-UNSATURATED ALDEHYDES; MICHAEL ADDITION; DOMINO REACTIONS; STEREOCENTERS; OXIDATION; ASPIDOPHYTINE; HAPLOPHYTINE; CHEMISTRY;
D O I：
10.1039/b922053d
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly enantioselective construction of delta- and gamma-lactone[2,3-b] piperidine skeletons was accomplished by tandem aza-Diels-Alder reaction-hemiacetal formation-oxidation from N-Tos-1-aza-1,3-butadienes and aliphatic dialdehydes.
引用
收藏
页码：755 / 757
页数：3
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