Meiotic recombination intermediates and mismatch repair proteins

被引:71
作者
Hoffmann, ER [1 ]
Borts, RH [1 ]
机构
[1] Univ Leicester, Dept Genet, Leicester LE1 7RH, Leics, England
关键词
D O I
10.1159/000080601
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Mismatch repair proteins are a highly diverse group of proteins that interact with numerous DNA structures during DNA repair and replication. Here we review data for the role of Msh4, Msh5, Mlh1, Mlh3 and Exo1 in crossing over. Based on the paradigm of interactions developed from studies of mismatch repair, we propose models for the mechanism of crossover implementation by Msh4/Msh5 and Mlh1/Mlh3. Copyright (C) 2004 S. Karger AG, Basel.
引用
收藏
页码:232 / 248
页数:17
相关论文
共 164 条
[1]   A role for the MutL homologue MLH2 in controlling heteroduplex formation and in regulating between two different crossover pathways in budding yeast [J].
Abdullah, MFF ;
Hoffmann, ER ;
Cotton, VE ;
Borts, RH .
CYTOGENETIC AND GENOME RESEARCH, 2004, 107 (3-4) :180-190
[2]   The coordinated functions of the E-coli MutS and MutL proteins in mismatch repair [J].
Acharya, S ;
Foster, PL ;
Brooks, P ;
Fishel, R .
MOLECULAR CELL, 2003, 12 (01) :233-246
[3]   Zip3 provides a link between recombination enzymes and synaptonemal complex proteins [J].
Agarwal, S ;
Roeder, GS .
CELL, 2000, 102 (02) :245-255
[4]   Genetic and biochemical analysis of Msh2p-Msh6p: Role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition [J].
Alani, E ;
Sokolsky, T ;
Studamire, B ;
Miret, JJ ;
Lahue, RS .
MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (05) :2436-2447
[5]  
Alani E, 1996, MOL CELL BIOL, V16, P5604
[6]   ANALYSIS OF WILD-TYPE AND RAD50 MUTANTS OF YEAST SUGGESTS AN INTIMATE-RELATIONSHIP BETWEEN MEIOTIC CHROMOSOME SYNAPSIS AND RECOMBINATION [J].
ALANI, E ;
PADMORE, R ;
KLECKNER, N .
CELL, 1990, 61 (03) :419-436
[7]   Differential timing and control of noncrossover and crossover recombination during meiosis [J].
Allers, T ;
Lichten, M .
CELL, 2001, 106 (01) :47-57
[8]   Intermediates of yeast meiotic recombination contain heteroduplex DNA [J].
Allers, T ;
Lichten, M .
MOLECULAR CELL, 2001, 8 (01) :225-231
[9]  
Anderson LK, 1999, GENETICS, V151, P1569
[10]   Systematic mutagenesis of the Saccharomyces cerevisiae MLH1 gene reveals distinct roles for Mlh1p in meiotic crossing over and in vegetative and meiotic mismatch repair [J].
Argueso, JL ;
Kijas, AW ;
Sarin, S ;
Heck, J ;
Waase, M ;
Alani, E .
MOLECULAR AND CELLULAR BIOLOGY, 2003, 23 (03) :873-886