Anti-PD-1/PD-L1 therapy for renal cell carcinoma: challenges in the development of predictive biomarkers

被引：3
作者：
Kato, Renpei [1 ]
Obara, Wataru [1 ]
机构：
[1] Iwate Med Univ, Dept Urol, Morioka, Iwate, Japan
来源：
EXPERT REVIEW OF ANTICANCER THERAPY | 2022年 / 22卷 / 07期
关键词：
anti-PD-1/PD-L1; therapy; biomarker; renal cell carcinoma; PD-L1; expression; peripheral blood biomarkers; CIRCULATING TUMOR DNA; CHECKPOINT; EXPRESSION;
D O I：
10.1080/14737140.2022.2087631
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：667 / 669
页数：3
相关论文
共 15 条
[1]  
Bilen MA, 2021, CLIN CANCER RES, V28, P738
[2]   Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma [J].
Braun, David A. ;
Hou, Yue ;
Bakouny, Ziad ;
Ficial, Miriam ;
Sant' Angelo, Miriam ;
Forman, Juliet ;
Ross-Macdonald, Petra ;
Berger, Ashton C. ;
Jegede, Opeyemi A. ;
Elagina, Liudmilla ;
Steinharter, John ;
Sun, Maxine ;
Wind-Rotolo, Megan ;
Pignon, Jean-Christophe ;
Cherniack, Andrew D. ;
Lichtenstein, Lee ;
Neuberg, Donna ;
Catalano, Paul ;
Freeman, Gordon J. ;
Sharpe, Arlene H. ;
McDermott, David F. ;
Van Allen, Eliezer M. ;
Signoretti, Sabina ;
Wu, Catherine J. ;
Shukla, Sachet A. ;
Choueiri, Toni K. .
NATURE MEDICINE, 2020, 26 (06) :909-+
[3]   Correlation of PD-L1 Tumor Expression and Treatment Outcomes in Patients with Renal Cell Carcinoma Receiving Sunitinib or Pazopanib: Results from COMPARZ, a Randomized Controlled Trial [J].
Choueiri, Toni K. ;
Figueroa, David J. ;
Fay, Andre P. ;
Signoretti, Sabina ;
Liu, Yuan ;
Gagnon, Robert ;
Deen, Keith ;
Carpenter, Christopher ;
Benson, Peter ;
Ho, Thai H. ;
Pandite, Lini ;
de Souza, Paul ;
Powles, Thomas ;
Motzer, Robert J. .
CLINICAL CANCER RESEARCH, 2015, 21 (05) :1071-1077
[4]   Evaluation of Clear Cell, Papillary, and Chromophobe Renal Cell Carcinoma Metastasis Sites and Association With Survival [J].
Dudani, Shaan ;
de Velasco, Guillermo ;
Wells, J. Connor ;
Gan, Chun Loo ;
Donskov, Frede ;
Porta, Camillo ;
Fraccon, Anna ;
Pasini, Felice ;
Lee, Jae Lyun ;
Hansen, Aaron ;
Bjarnason, Georg A. ;
Beuselinck, Benoit ;
Pal, Sumanta K. ;
Yuasa, Takeshi ;
Kroeger, Nils ;
Kanesvaran, Ravindran ;
Reaume, M. Neil ;
Canil, Christina ;
Choueiri, Toni K. ;
Heng, Daniel Y. C. .
JAMA NETWORK OPEN, 2021, 4 (01)
[5]   Treatment Beyond Progression in Patients with Advanced Renal Cell Carcinoma Treated with Nivolumab in CheckMate 025 [J].
Escudier, Bernard ;
Motzer, Robert J. ;
Sharma, Padmanee ;
Wagstaff, John ;
Plimack, Elizabeth R. ;
Hammers, Hans J. ;
Donskov, Frede ;
Gurney, Howard ;
Sosman, Jeffrey A. ;
Zalewski, Pawel G. ;
Harmenberg, Ulrika ;
McDermott, David F. ;
Choueiri, Toni K. ;
Richardet, Martin ;
Tomita, Yoshihiko ;
Ravaud, Alain ;
Doan, Justin ;
Zhao, Huanyu ;
Hardy, Helene ;
George, Saby .
EUROPEAN UROLOGY, 2017, 72 (03) :368-376
[6]   Evidence and Clinical Relevance of Tumor Flare in Patients Who Discontinue Tyrosine Kinase Inhibitors for Treatment of Metastatic Renal Cell Carcinoma [J].
Iacovelli, Roberto ;
Massari, Francesco ;
Albiges, Laurence ;
Loriot, Yohann ;
Massard, Christophe ;
Fizazi, Karim ;
Escudier, Bernard .
EUROPEAN UROLOGY, 2015, 68 (01) :154-160
[7]   Potential of circulating tumor DNA as a predictor of therapeutic responses to immune checkpoint blockades in metastatic renal cell carcinoma [J].
Kim, Yeon Jeong ;
Kang, Yumi ;
Kim, Jun Seop ;
Sung, Hyun Hwan ;
Jeon, Hwang Gyun ;
Jeong, Byong Chang ;
Seo, Seong Il ;
Jeon, Seong Soo ;
Lee, Hyun Moo ;
Park, Donghyun ;
Park, Woong-Yang ;
Kang, Minyong .
SCIENTIFIC REPORTS, 2021, 11 (01)
[8]   Immune-based combinations for the treatment of metastatic renal cell carcinoma: a meta-analysis of randomised clinical trials [J].
Massari, Francesco ;
Rizzo, Alessandro ;
Mollica, Veronica ;
Rosellini, Matteo ;
Marchetti, Andrea ;
Ardizzoni, Andrea ;
Santoni, Matteo .
EUROPEAN JOURNAL OF CANCER, 2021, 154 :120-127
[9]   Molecular Subsets in Renal Cancer Determine Outcome to Checkpoint and Angiogenesis Blockade [J].
Motzer, Robert J. ;
Banchereau, Romain ;
Hamidi, Habib ;
Powles, Thomas ;
McDermott, David ;
Atkins, Michael B. ;
Escudier, Bernard ;
Liu, Li-Fen ;
Leng, Ning ;
Abbas, Alexander R. ;
Fan, Jinzhen ;
Koeppen, Hartmut ;
Lin, Jennifer ;
Carroll, Susheela ;
Hashimoto, Kenji ;
Mariathasan, Sanjeev ;
Green, Marjorie ;
Tayama, Darren ;
Hegde, Priti S. ;
Schiff, Christina ;
Huseni, Mahrukh A. ;
Rini, Brian .
CANCER CELL, 2020, 38 (06) :803-+
[10]   Avelumab plus axitinib versus sunitinib in advanced renal cell carcinoma: biomarker analysis of the phase 3 JAVELIN Renal 101 trial [J].
Motzer, Robert J. ;
Robbins, Paul B. ;
Powles, Thomas ;
Albiges, Laurence ;
Haanen, John B. ;
Larkin, James ;
Mu, Xinmeng Jasmine ;
Ching, Keith A. ;
Uemura, Motohide ;
Pal, Sumanta K. ;
Alekseev, Boris ;
Gravis, Gwenaelle ;
Campbell, Matthew T. ;
Penkov, Konstantin ;
Lee, Jae Lyun ;
Hariharan, Subramanian ;
Wang, Xiao ;
Zhang, Weidong ;
Wang, Jing ;
Chudnovsky, Aleksander ;
di Pietro, Alessandra ;
Donahue, Amber C. ;
Choueiri, Toni K. .
NATURE MEDICINE, 2020, 26 (11) :1733-+
12