Enhancing cyst-like lesions of the white matter in tuberous sclerosis complex: a novel neuroradiological finding

被引：5

作者：

D'Amico, Alessandra ^{[1
]}

Perillo, Teresa ^{[2
]}

Russo, Carmela ^{[3
]}

Ugga, Lorenzo ^{[2
]}

Melis, Daniela ^{[4
]}

Santoro, Claudia ^{[5
,6
]}

Piluso, Giulio ^{[7
]}

Cinalli, Giuseppe ^{[8
]}

机构：

[1] Tortorella Private Hosp, Dept Radiol, Salerno, Italy

[2] Univ Naples Federico II, Dept Adv Biomed Sci, Via S Pansini 5, I-80131 Naples, Italy

[3] Santobono Pausilipon Childrens Hosp, Dept Neurosci, Pediat Neuroradiol, Naples, Italy

[4] Univ Salerno, Sect Pediat, Dept Med Surg & Dent, Scuola Med Salernitana, Via Salvador Allende 43, I-84081 Baronissi, Italy

[5] Univ Campania Luigi Vanvitelli, Dept Phys & Mental Hlth & Prevent Med, Clin Child & Adolescent Neuropsychiat, Naples, Italy

[6] Univ Campania Luigi Vanvitelli, Dept Women Children & Gen & Specialized Surg, Naples, Italy

[7] Univ Campania Luigi Vanvitelli, Dept Precis Med, Via Luigi De Crecchio 7, I-80138 Naples, Italy

[8] Santobono Pausilipon Childrens Hosp, Dept Pediat Neurosurg, Naples, Italy

来源：

NEURORADIOLOGY | 2021年 / 63卷 / 06期

关键词：

Tuberous sclerosis complex; Pediatric neuroradiology; Magnetic resonance imaging; Phakomatosis;

D O I：

10.1007/s00234-021-02647-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Tuberous sclerosis complex (TSC) is an autosomal dominant condition clinically presenting with heterogenous clinical features. Multiple neuroradiological manifestations have been associated with TSC, such as tubers, radial migration lines, subependymal nodules, subependymal giant cell astrocytomas, and cyst-like lesions of the white matter (CLLWMs). The latter have been described as non-enhancing well-defined cysts whose pathogenesis is still unknown. We describe 2 TSC patients with CLLWM showing contrast enhancement after Gadolinium injection, a previously unreported entity.

引用

页码：971 / 974

页数：4

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