Proneness to psychological distress and risk of Alzheimer disease in a biracial community

被引：168
作者：
Wilson, RS
Barnes, LL
Bennett, DA
Li, Y
Bienias, JL
de Leon, CFM
Evans, DA
机构：
[1] Rush Univ, Med Ctr, Armour Acad Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
[2] Rush Univ, Med Ctr, Rush Inst Hlth Aging, Chicago, IL 60612 USA
[3] Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA
[4] Rush Univ, Med Ctr, Dept Internal Med, Chicago, IL 60612 USA
[5] Rush Univ, Med Ctr, Dept Psychol, Chicago, IL 60612 USA
来源：
NEUROLOGY | 2005年 / 64卷 / 02期
关键词：
D O I：
10.1212/01.WNL.0000149525.53525.E7
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Persons without dementia residing in a biracial community completed a brief scale of proneness to psychological distress, and 1,064 were subsequently examined for incident Alzheimer disease ( AD) 3 to 6 years later. In analyses controlling for selected demographic and clinical variables, persons prone to distress were 2.4 times more likely to develop AD than persons not distress prone. This effect was substantially stronger in white persons compared to African Americans.
引用
收藏
页码：380 / 382
页数：3
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