Computational protein design: Advances in the design and redesign of biomolecular nanostructures

被引：24

作者：

Saven, Jeffery G. ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Philadelphia, PA 19104 USA

来源：

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE | 2010年 / 15卷 / 1-2期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

Computational protein design; Nanostructures; Structural biology; Self-assembly; Protein library; Protein symmetry; Nanoparticle; Optoelectronic; Cofactor; Porphyrin; Membrane protein; DE-NOVO DESIGN; ARTIFICIAL DIIRON PROTEINS; DYNAMICS; STABILIZATION; MEMBRANES; PEPTIDE;

D O I：

10.1016/j.cocis.2009.06.002

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Computational protein design facilitates the continued development of methods for the design of biomolecular structure, sequence and function. Recent applications include the design of novel protein sequences and structures, proteins incorporating nonbiological components, protein assemblies, soluble variants of membrane proteins, and proteins that modulate membrane function. (C) 2009 Elsevier Ltd. All rights reserved.

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页码：13 / 17

页数：5

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