Phenotype of acute respiratory syncytial virus induced lower respiratory tract illness in infancy and subsequent morbidity

被引：14

作者：

Elphick, H. E.

Ritson, S.

Rigby, A. S.

Everard, M. L. ^{[1
]}

机构：

[1] Sheffield Childrens Hosp, Western Bank, Sheffield S10 2TH, S Yorkshire, England

[2] Sheffield Childrens Hosp, Div Child Hlth, Sheffield S10 2TH, S Yorkshire, England

[3] Univ Hull, Acad Dept Cardiol, Kingston Upon Hull, Yorks, England

来源：

ACTA PAEDIATRICA | 2007年 / 96卷 / 02期

关键词：

atopy; infant; morbidity; phenotype; RSV; wheeze;

D O I：

10.1111/j.1651-2227.2007.00082.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The objective of this study was to investigate the association hypothesis that outcome following respiratory syncytial virus (RSV) induced bronchiolitis (RSVB) and RSV induced wheeze (RSVW) are different. At 3 years respiratory symptoms were more common in those with RSV infection than the control group but there was no increase in allergic sensitisation (11% vs 10%). Those with RSVW were more likely to have evidence of allergic sensitisation when compared with RSVB subjects (22% vs 7%), and have increased symptoms and increased use of inhaled steroids. Conclusion: The data argue that RSV infection during infancy does not induce allergic asthma and that host factors rather than the virus determine long-term outcomes.

引用

页码：307 / 309

页数：3

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