Palladium-catalysed methylation of aryl halides in ionic liquids with stabilized AlMe3

被引：9

作者：

Conte, Valeria ^{[1
]}

Fiorani, Giulia ^{[1
]}

Floris, Barbara ^{[1
]}

Galloni, Pierluca ^{[1
]}

Woodward, Simon ^{[2
]}

机构：

[1] Univ Roma Tor Vergata, Dipartimento Sci & Tecnol Chim, I-00133 Rome, Italy

[2] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

来源：

APPLIED CATALYSIS A-GENERAL | 2010年 / 381卷 / 1-2期

基金：

英国工程与自然科学研究理事会;

关键词：

Methylation; Pd-catalysis; Ionic liquids; Cross-coupling reactions; Trialkylaluminum reagents; DABAL-Me-3; VINYL HALIDES; ORGANOALUMINUM;

D O I：

10.1016/j.apcata.2010.04.005

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A new protocol for the methylation of aryl halides using the AlMe3 analogue DABAL-Me-3 in a VOC/IL biphasic system is described. Very good isolated yields and chemoselectivities (methylation vs homocoupling), were observed in alkylmethylimidazolium and DABCO-based ILs, in presence of a bulky substituted phosphine (XPhos) and the structurally related sulfonated phosphine (XPhosSO(3)H). Recycling experiments of the IL-catalyst systems were satisfactory only in case of the butyldimethylimidazolium IL due to catalyst loss to the VOC phase. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：161 / 168

页数：8

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