CT Perfusion and Multiphase CT Angiography in Malignant Brain Edema Prediction in Patients with Acute Ischemic Stroke

被引：0
作者：
Volny, O. [1 ,2 ]
Cimflova, P. [1 ,3 ]
d'Esterre, C. D. [4 ]
机构：
[1] FN Sv Anny Brne, ICRC Mezinarodni Ctr Klin Vyzkumu, Pekarska 53, Brno 65691, Czech Republic
[2] LF MU & FN Sv Anny Brne, Neurol Klin 1, Brno, Czech Republic
[3] LF MU & FN Sv Anny Brne, Klin Zobrazovacich Metod, Brno, Czech Republic
[4] Univ Calgary, Hotchkiss Brain Inst, Dept Clin Neurosci, Calgary Stroke Program, Calgary, AB T2N 1N4, Canada
来源：
CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE | 2016年 / 79卷 / 02期
关键词：
acute ischemic stroke; brain oedema; CT perfusion; CTA angiography; dural sinuses; MIDDLE CEREBRAL-ARTERY; BARRIER PERMEABILITY; INFARCTION;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
We explore the predictive value of CT perfusion parameters (permeability surface area, cerebral blood flow, cerebral blood volume) and multiphase CT angiography (clot localization, leptomeningeal collaterals and dural sinuses morphology) in the development of malignant brain oedema in patients with acute proximal occlusion of the middle cerebral artery. Patients from the multicentre prospective study PROVE -IT (Precise and Rapid assessment of collaterals using multi -phase CTA in the triage of patients with acute ischemic stroke for IV or IA Therapy; n = 200) were analysed. Primary outcome was evaluated by midline shift >= 5 mm on a follow-up CT/MRI. A CBV threshold of 1.76 ml/100 g had the highest sensitivity and specificity of for the midline shift. There was no significant difference between the two groups in analysed CT perfusion parameters calculated for the entire ischemic region.
引用
收藏
页码：213 / 217
页数：5
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