Annulation of m-Substituted Aromatic Ketones with Diphenylacetylene Catalyzed by Ruthenium: A Reliable Route to Substituted Naphthalene Derivatives

被引：2

作者：

Cui, Y. ^{[2
]}

Wang, R. ^{[1
]}

Yang, C. ^{[2
]}

Wang, A. ^{[2
]}

Jing, Y. ^{[1
]}

Zhang, S. ^{[1
]}

机构：

[1] Yulin Normal Univ, Sch Chem & Food Sci, Guangxi Key Lab Agr Resources Chem & Biotechnol, Yulin 537000, Guangxi, Peoples R China

[2] Dalian Univ, Coll Environm & Chem Engn, Dalian 116600, Liaoning, Peoples R China

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2022年 / 92卷 / 12期

关键词：

naphthalene derivatives; annulation; ruthenium-catalyzed reactions; m-substituted aromatic ketones; C-H bond functionalization; H BOND FUNCTIONALIZATIONS; INTERNAL ALKYNES; DIRECTING GROUP; CYCLIZATION; ACTIVATION; INHIBITORS; INDOLES; AMIDES;

D O I：

10.1134/S107036322212043X

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Ru-catalyzed annulation reaction of m-substituted aromatic ketones with diphenylacetylene to prepare polysubstituted naphthalene derivatives was reported. m-Substituted aromatic ketones have two different ortho C-H bonds; the experimental results and theoretical calculation both illustrate that m-substituted aromatic ketones use less hindered C-H bond to participate in the cyclization. The method has the advantages of forming two new carbon-carbon bonds in one single step, wide substrates tolerance, and mild reaction conditions.

引用

页码：2899 / 2909

页数：11

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