Microencapsulation techniques, factors influencing encapsulation efficiency

被引:474
作者
Jyothi, N. Venkata Naga [1 ]
Prasanna, P. Muthu [1 ]
Sakarkar, Suhas Narayan [2 ]
Prabha, K. Surya [1 ]
Ramaiah, P. Seetha [1 ]
Srawan, G. Y. [1 ]
机构
[1] Hindu Coll Pharm, Dept Pharmaceut, Guntur 522002, Andhra Pradesh, India
[2] Millennium Coll Pharm, Bhopal, India
关键词
Microencapsulation; encapsulation efficiency; coacervation; supercritical fluids; POLY(D; L-LACTIC-CO-GLYCOLIC ACID) MICROSPHERES; PLGA MICROSPHERES; MOLECULAR-WEIGHT; CROSS-LINKING; RELEASE; STABILITY; COACERVATION; FORMULATION; PARAMETERS; DELIVERY;
D O I
10.3109/02652040903131301
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Microencapsulation is one of the quality preservation techniques of sensitive substances and a method for production of materials with new valuable properties. Microencapsulation is a process of enclosing micron-sized particles in a polymeric shell. There are different techniques available for the encapsulation of drug entities. The encapsulation efficiency of the microparticle or microsphere or microcapsule depends upon different factors like concentration of the polymer, solubility of polymer in solvent, rate of solvent removal, solubility of organic solvent in water, etc. The present article provides a literature review of different microencapsulation techniques and different factors influencing the encapsulation efficiency of the microencapsulation technique.</.
引用
收藏
页码:187 / 197
页数:11
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