Inflammatory breast cancer: An overview

被引:100
作者
van Uden, D. J. P. [1 ]
van Laarhoven, H. W. M. [2 ]
Westenberg, A. H. [3 ]
de Wilt, J. H. W. [4 ]
Blanken-Peeters, C. F. J. M. [5 ]
机构
[1] Canisius Wilhelmina Hosp, Dept Surg, NL-6500 GS Nijmegen, Netherlands
[2] Univ Amsterdam, Acad Med Ctr, NL-1100 DD Amsterdam, Netherlands
[3] Inst Radiat Oncol, NL-6800 JD Arnhem, Netherlands
[4] Radboud Univ Nijmegen, Med Ctr, Dept Surg, NL-6525 GA Nijmegen, Netherlands
[5] Rijnstate Hosp, Dept Surg, NL-6815 AD Arnhem, Netherlands
关键词
Inflammatory breast cancer; Molecular characteristics; Treatment; Surgery; END RESULTS PROGRAM; NEOADJUVANT CHEMOTHERAPY; GROWTH-FACTOR; CARCINOMA INCIDENCE; PHASE-II; EXPRESSION; SURVIVAL; RECEPTOR; RECONSTRUCTION; EPIDEMIOLOGY;
D O I
10.1016/j.critrevonc.2014.09.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Inflammatory breast cancer (IBC) is the most aggressive entity of breast cancer. Management involves coordination of multidisciplinary management and usually includes neoadjuvant chemotherapy, ablative surgery if a tumor-free resection margin is expected and locoregional radiotherapy. This multimodal therapeutic approach has significantly improved patient survival. However, the median overall survival among women with IBC is still poor. By elucidating the biologic characteristics of IBC, new treatment options may become available. We performed a comprehensive review of the English-language literature on IBC through computerized literature searches. The objective of the current review is to present an overview of the literature related to the biology, imaging and multidisciplinary treatment of inflammatory breast cancer. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:116 / 126
页数:11
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