Lipoinjection in the paralyzed feline vocal fold: Study of graft survival

被引:18
作者
Saccogna, PW
Werning, JW
Setrakian, S
Strauss, M
机构
[1] CASE WESTERN RESERVE UNIV,SCH MED,DEPT OTOLARYNGOL HEAD & NECK SURG,CLEVELAND,OH
[2] CASE WESTERN RESERVE UNIV,SCH MED,DEPT PATHOL,CLEVELAND,OH
关键词
D O I
10.1016/S0194-5998(97)70015-9
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Six adult domestic strain cats were used to study the long-term histologic outcome of injected autologous fat for augmentation of the paralyzed vocal fold. Each animal had surgically induced left vocal cord paralysis via sectioning of the recurrent laryngeal nerve, followed by injection of 0.1 to 0.2 mi of autologous fat into the paralyzed vocal fold. The animals were killed at 6 weeks, and at Lt, 6, 8, and 12 months after the injection. Photographic and videolaryngoscopic data were obtained, Histologic studies of the larynges were performed. The results documented histologic viability and persistence of a portion of the injected adipose tissue graft at 8 months after the injection, but only minimal graft survival at 12 months. The outcome suggests that autologous lipoinjection has potential use for short-term (several months) augmentation of the paralyzed vocal cord. Further investigation is warranted before recommending this technique for such use or as an alternative to currently available long-term injectable laryngeal biomaterials.
引用
收藏
页码:465 / 470
页数:6
相关论文
共 28 条
[1]  
AGRIS J, 1987, AM J COSMETIC SURG, V4, P95
[2]  
ARNOLD GE, 1962, ARCHIV OTOLARYNGOL, V76, P358
[3]   HISTOPATHOLOGIC EVALUATION OF ADIPOSE AUTOGRAFTS IN A RABBIT EAR MODEL [J].
BARTYNSKI, J ;
MARION, MS ;
WANG, TD .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 1990, 102 (04) :314-321
[4]   VOCAL CORD AUGMENTATION WITH AUTOGENOUS FAT [J].
BRANDENBURG, JH ;
KIRKHAM, W ;
KOSCHKEE, D .
LARYNGOSCOPE, 1992, 102 (05) :495-500
[5]  
Campbell GL, 1987, AM J COSMET SURG, V4, P89, DOI [10.1177/074880688700400202, DOI 10.1177/074880688700400202]
[6]  
CHAJCHIR A, 1989, PLAST RECONSTR SURG, V84, P921, DOI 10.1097/00006534-198912000-00009
[7]   INTRACORDAL INJECTION OF TEFLON IN TREATMENT OF 135 PATIENTS WITH DYSPHONIA [J].
DEDO, HH ;
URREA, RD ;
LAWSON, L .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1973, 82 (05) :661-667
[8]   TRANSPLANTATION OF PURIFIED AUTOLOGOUS FAT - A 3-YEAR FOLLOW-UP IS DISAPPOINTING [J].
ERSEK, RA .
PLASTIC AND RECONSTRUCTIVE SURGERY, 1991, 87 (02) :219-227
[9]  
Ford Charles N., 1991, PHONOSURGERY ASSESSM
[10]   A PRELIMINARY-STUDY OF INJECTABLE COLLAGEN IN HUMAN VOCAL FOLD AUGMENTATION [J].
FORD, CN ;
BLESS, DM .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 1986, 94 (01) :104-112