Magnifying chromoscopy, a novel and useful technique for colonoscopy in ulcerative colitis

被引：6

作者：

Ando, Takafumi ^{[1
]}

Takahashi, Hironao ^{[1
]}

Watanabe, Osamu ^{[1
]}

Maeda, Osamu ^{[1
]}

Ishiguro, Kazuhiro ^{[1
]}

Ishikawa, Daisuke ^{[1
]}

Hasegawa, Motofusa ^{[1
]}

Ohmiya, Naoki ^{[1
]}

Niwa, Yasumasa ^{[1
]}

Goto, Hidemi ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Med, Dept Gastroenterol, Showa Ku, Nagoya, Aichi 4668550, Japan

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2007年 / 13卷 / 18期

关键词：

ulcerative colitis; histopathology; conventional colonoscopy; magnifying colonoscopy; ulcerative colitis-associated colorectal cancer; INFLAMMATORY-BOWEL-DISEASE; LOW-GRADE DYSPLASIA; TERM FOLLOW-UP; COLORECTAL-CANCER; COLON-CANCER; RECTAL BIOPSY; INTRAEPITHELIAL NEOPLASIA; SURVEILLANCE COLONOSCOPY; NATURAL-HISTORY; CARCINOMA;

D O I：

10.3748/wjg.v13.i18.2523

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Ulcerative colitis (UC) is a chronic inflammatory bowel disorder characterized by exacerbations and remissions. The degree of inflammation as assessed by conventional colonoscopy is a reliable parameter of disease activity. However, even when conventional colonoscopy suggests remission and normal mucosal findings, microscopic abnormalities may persist, and relapse may occur later. Patients with long-standing, extensive ulcerative colitis have an increased risk of developing colorectal cancer. Ulcerative colitis-associated colorectal cancer is characterized by an early age at onset, poorly differentiated tumor cells, mucinous carcinoma, and multiple lesions. Early detection of dysplasia and colitic cancer is thus a prerequisite for survival. A relatively new method, magnifying chromoscopy, is thought to be useful for the early detection and diagnosis of dysplasia and colitic cancer, as well as the prediction of relapse. (C) 2007 The WJG Press. All rights reserved.

引用

页码：2523 / 2528

页数：6

共 75 条

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