Malaria diagnostics: now and the future

被引:38
作者
Chiodini, Peter L. [1 ,2 ]
机构
[1] Hosp Trop Dis, London WC1E 6JB, England
[2] London Sch Hyg & Trop Med, London WC1E 7HT, England
关键词
malaria; microscopy; rapid diagnostic tests; nucleic acid detection; PLASMODIUM-FALCIPARUM DNA; AMPLIFICATION KIT; HUMAN INFECTIONS; PARASITEMIA; IDENTIFY; TESTS; PCR;
D O I
10.1017/S0031182014001371
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Light microscopy of stained blood films is still the mainstay of malaria diagnosis in many regions, but its pre-eminence is threatened by accurate and sensitive rapid diagnostic tests (RDTs) based on immunochromatography which are now widely used in the field. In well-resourced regions, nucleic acid detection easily out performs microscopy and RDTs. This paper reviews the main in vitro methods for parasite detection and considers future trends in diagnostics, both for sophisticated laboratory settings and for field use.
引用
收藏
页码:1873 / 1879
页数:7
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