Determination of mercury cation using electrode modified with phosphorothioate oligonucleotide

被引：12

作者：

Bala, Agnieszka ^{[1
]}

Gorski, Lukasz ^{[1
]}

机构：

[1] Warsaw Univ Technol, Fac Chem, Dept Microbioanalyt, Inst Biotechnol, Noakowskiego 3, PL-00664 Warsaw, Poland

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2016年 / 230卷

关键词：

Electrochemical sensor; Phosphorothioate oligonucleotide; Metal ion determination; HG2+;

D O I：

10.1016/j.snb.2016.02.103

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel electrochemical biosensor for the determination of mercury ion is described. The receptor layer was formed on glassy carbon electrode by adsorption of phosphorothioate oligonucleotide (PTO). The presence of sulfur atom in the backbone of modified nucleotide allows for strong interaction with Hg2+. The optimized sensor distinguishes itself with high selectivity towards mercury ions and lower detection limit of 2.34 x 10(-11) mol L-1. For tested PTO sequence, it was possible to determine the linear response in the Hg2+ concentration range of 10(-11)-10(-7) mol L-1. (C) 2016 Elsevier B.V. All rights reserved.

引用

收藏

页码：731 / 735

页数：5

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