Linear dichroism of biomolecules: which way is up?

被引：36

作者：

Dafforn, TR ^{[1
]}

Rodger, A

机构：

[1] Univ Birmingham, Dept Biosci, Birmingham B15 2TT, W Midlands, England

[2] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2004年 / 14卷 / 05期

关键词：

D O I：

10.1016/j.sbi.2004.08.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Understanding the organization of molecules in naturally occurring ordered arrays (e.g. membranes, protein fibres and DNA strands) is of great importance to understanding biological function. Unfortunately, few biophysical techniques provide detailed structural information on these non-crystalline systems. UV, visible and IR linear dichroism have the potential to provide such information. Recent advances in technology and simulations allow this potential to be fulfilled, and can now provide a detailed understanding of the molecular mechanisms of such fundamental biological processes as amyloid fibre formation and membrane protein folding.

引用

页码：541 / 546

页数：6

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