Neurocognitive sequelae of pediatric sickle cell disease: A review of the literature

被引：106

作者：

Berkelhammer, Leslie D. ^{[1
]}

Williamson, Adrienne L. ^{[1
]}

Sanford, Stacy D. ^{[1
]}

Dirksen, Courtney L. ^{[1
]}

Sharp, William G. ^{[1
]}

Margulies, Allison S. ^{[1
]}

Prengler, Rebecca A. ^{[1
]}

机构：

[1] St Jude Childrens Res Hosp, Div Behav Med, Memphis, TN 38105 USA

来源：

CHILD NEUROPSYCHOLOGY | 2007年 / 13卷 / 02期

关键词：

sickle cell disease; pediatric neuropsychology; literature review; children; cognitive rehabilitation; neuroimaging; executive function;

D O I：

10.1080/09297040600800956

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

This literature review summarizes all studies relating neuropsychological performance to neuroimaging findings in pediatric sickle cell disease (N= 28; published 1991 - 2005). Although inconsistencies exist within and across domains, deficits in intelligence ( IQ), attention and executive functions, memory, language, visuomotor abilities, and academic achievement have been identified. Overall neurocognitive compromise was revealed to be related to the level of neurological injury and the location of silent infarct. Attentional and executive dysfunction is prevalent and related to frontal lobe abnormalities.

引用

页码：120 / 131

页数：12

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