Diaphragm dysfunction in severe COVID-19 as determined by neuromuscular ultrasound

被引：59

作者：

Farr, Ellen ^{[1
,2
,3
]}

Wolfe, Alexis R. ^{[1
,4
]}

Deshmukh, Swati ^{[5
]}

Rydberg, Leslie ^{[2
,3
]}

Soriano, Rachna ^{[2
,3
]}

Walter, James M. ^{[4
]}

Boon, Andrea J. ^{[6
,7
]}

Wolfe, Lisa F. ^{[4
,8
]}

Franz, Colin K. ^{[2
,3
,8
]}

机构：

[1] Northwestern Univ, Mcgaw Med Ctr, Feinberg Sch Med, Chicago, IL 60611 USA

[2] Shirley Ryan Abil Lab, 26 North,355 E Erie St, Chicago, IL 60611 USA

[3] Northwestern Univ, Feinberg Sch Med, Dept Phys Med & Rehabil, Chicago, IL 60611 USA

[4] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Pulm & Crit Care, Chicago, IL 60611 USA

[5] Northwestern Univ, Feinberg Sch Med, Dept Radiol, Chicago, IL 60611 USA

[6] Mayo Clin, Dept Phys Med & Rehabil, Rochester, MN USA

[7] Mayo Clin, Dept Neurol, Rochester, MN USA

[8] Northwestern Univ, Feinberg Sch Med, Ken & Ruth Davee Dept Neurol, Chicago, IL 60611 USA

来源：

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY | 2021年 / 8卷 / 08期

关键词：

D O I：

10.1002/acn3.51416

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Many survivors from severe coronavirus disease 2019 (COVID-19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe post-COVID-19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one sonographic abnormality of diaphragm muscle structure or function. This corresponded to a significant reduction in diaphragm muscle contractility as represented by thickening ratio (muscle thickness at maximal inspiration/end-expiration) for the post-COVID-19 compared to non-COVID-19 cohorts. These findings may shed new light on neuromuscular respiratory dysfunction as a contributor to prolonged functional impairments after hospitalization for post-COVID-19.

引用

页码：1745 / 1749

页数：5

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