Recent advances in therapeutic chalcones

被引：180
|
作者：
Ni, LM [1 ]
Meng, CQ [1 ]
Sikorski, JA [1 ]
机构：
[1] AtheroGenet Inc, Alpharetta, GA 30004 USA
来源：
EXPERT OPINION ON THERAPEUTIC PATENTS | 2004年 / 14卷 / 12期
关键词：
1,3-diphenyl-2-propen-1-one; alpha; beta-unsaturated ketone; antibacterial; anticancer; anti-infective; anti-inflammatory; antimalarial; antioxidant; chalcone;
D O I：
10.1517/13543776.14.12.1669
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Naturally-occurring and synthetic chalcone compounds have shown promising biological activity and safety profiles and have the potential to be developed as, or more properly, serve as lead compounds for, the discovery of antioxidant, anti-inflammatory, anticancer or anti-infective agents. Mechanisms of the diverse activities observed with chalcone compounds are not well-defined. This review highlights recent developments and patent activities of chalcones with various therapeutic properties.
引用
收藏
页码：1669 / 1691
页数：23
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