Tocopherols, tocotrienols and tocomonoenols: Many similar molecules but only one vitamin E

被引:104
作者
Azzi, Angelo [1 ]
机构
[1] Tufts Univ, Sackler Sch Grad Biomed Pharmacol & Drug Dev Prog, 75 Kneeland St, Boston, MA 02111 USA
关键词
ALPHA-TOCOPHEROL; GENE-TRANSCRIPTION;
D O I
10.1016/j.redox.2019.101259
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The aim of this article is to correct a very general error in scientific articles, in textbooks and in the Internet that has become an accepted fact. In this literature, the term "vitamin E. is used for several similar molecules (both tocopherols and tocotrienols) that have never been shown to have vitamin property, i.e. a protective effect against the human deficiency disease. In fact, the name "vitamin E. should only be used to define molecules that prevent the human deficiency disease "Ataxia with Vitamin E Deficiency" (AVED). Only one such molecule is known, alpha-tocopherol. This error may confuse consumers as well as medical doctors, who prescribe vitamin E without realizing that the current use of the name includes molecules of unknown, if not unwanted functions.
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页数:4
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