Chemical avulsion with urea nail lacquer

被引：13

作者：

Baran, R

Tosti, A

机构：

[1] Nail Dis Ctr, F-06400 Cannes, France

[2] Univ Bologna, Ist Clin Dermatol, Bologna, Italy

来源：

JOURNAL OF DERMATOLOGICAL TREATMENT | 2002年 / 13卷 / 04期

关键词：

chemical avulsion; onychomycosis; transungual drug delivery system; treatment urea;

D O I：

10.1080/09546630212345672

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

BACKGROUND: Among the therapeutic possibilities for onychomycosis, chemical nail avulsion is a logical approach to the eradication of the pathogen. METHODS: A new formulation was used as a nail lacquer containing 40% urea in a film-forming solution in 10 patients presenting with onychomycosis. The urea nail lacquer was applied with a brush twice a day for 1 week by the patient and for a further week in two patients presenting total dystrophic onychomycosis. RESULTS: This transungual delivery system weakens the nail plate/ nail bed attachment in the diseased area. CONCLUSION: The urea nail lacquer is comfortable for the patient and allows easy removal of the affected part of the fungal nail plate.

引用

页码：161 / 164

页数：4

共 9 条

[1]

Baran R, 1996, ACTA DERM-VENEREOL, V76, P82

[2] PARTIAL SURGICAL AVULSION OF THE NAIL IN ONYCHOMYCOSIS [J].

BARAN, R ;

HAY, RJ .

CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1985, 10 (05) :413-418

[3]

Baran R., 1999, ONYCHOMYCOSIS

[4] EFFICACY AND SAFETY OF BIFONAZOLE UREA IN THE 2-PHASE TREATMENT OF ONYCHOMYCOSIS [J].

BONIFAZ, A ;

GUZMAN, A ;

GARCIA, C ;

SOSA, J ;

SAUL, A .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 1995, 34 (07) :500-503

[5]

DORN M, 1980, HAUTARZT, V31, P30

[6]

HAY RJ, 1986, SUPERFICIAL FUNGAL I, P23

[7]

Roberts DT, 1998, BRIT J DERMATOL, V138, P189, DOI 10.1046/j.1365-2133.1998.02050.x

[8]

SOUTH DA, 1980, CUTIS, V25, P609

[9]

TORRESRODRIGUEZ JM, 1991, MYCOSES, V34, P499, DOI 10.1111/j.1439-0507.1991.tb00867.x

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