Prophylactic Erythropoietin for Neuroprotection in Very Preterm Infants: A Meta-Analysis Update

被引：9
作者：
Fischer, Hendrik S. [1 ]
Reibel, Nora J. [1 ]
Buhrer, Christoph [1 ]
Dame, Christof [1 ]
机构：
[1] Charite Univ Med Berlin, Dept Neonatol, Berlin, Germany
来源：
FRONTIERS IN PEDIATRICS | 2021年 / 9卷
关键词：
erythropoietin; meta-analysis; neurodevelopment; neuroprotection; VLBW and ELBW infants; RECOMBINANT-HUMAN-ERYTHROPOIETIN; RANDOMIZED-TRIAL; OUTCOMES; AGE;
D O I：
10.3389/fped.2021.657228
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
A meta-analysis update of randomized controlled trials investigating recombinant human erythropoietin suggests improved neurodevelopmental outcome in preterm infants. There was substantial heterogeneity, which could be ascribed to a single trial. Exclusion of this trial featuring a high risk of bias abolished heterogeneity and any effects of recombinant human erythropoietin treatment.
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