Hemosiderosis with diabetes mellitus in untransfused hemoglobin H disease

被引：0

作者：

Chim, CS ^{[1
]}

Chan, V ^{[1
]}

Todd, D ^{[1
]}

机构：

[1] Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 1998年 / 57卷 / 02期

关键词：

HbH-CS; hemosiderosis; diabetes mellitus;

D O I：

10.1002/(SICI)1096-8652(199802)57:2<160::AID-AJH12>3.0.CO;2-G

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 37-year-old untransfused, non-drinking man with Hemoglobin H-CS disease presented with insulin-dependent diabetes mellitus, markedly elevated serum ferritin level, and marked iron deposition in hepatocytes. He did not carry either of the two common mutations of the HLA-H gene for hereditary hemochromatosis, namely, Cys282Tyr and His68Asp, nor did he have the associated HLA marker (HLA-A3, B7 nor B-14) for the disease. Patient with HbH disease should be monitored for iron overload. (C) 1997 Wiley-Liss, Inc.

引用

页码：160 / 163

页数：4

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