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Korea Univ, Dept Internal Med, Inst Digest Dis & Nutr, Div Gastroenterol & Hepatol,Anam Hosp,Coll Med, Seoul 136705, South Korea Korea Univ, Dept Internal Med, Inst Digest Dis & Nutr, Div Gastroenterol & Hepatol,Anam Hosp,Coll Med, Seoul 136705, South Korea