Conversion of amino-acid sequence in proteins to classical music: search for auditory patterns

被引:31
作者
Takahashi, Rie [1 ]
Miller, Jeffrey H.
机构
[1] Univ Calif Los Angeles, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Mol Biol Inst, Los Angeles, CA 90095 USA
关键词
D O I
10.1186/gb-2007-8-5-405
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
We have converted genome-encoded protein sequences into musical notes to reveal auditory patterns without compromising musicality. We derived a reduced range of 13 base notes by pairing similar amino acids and distinguishing them using variations of three-note chords and codon distribution to dictate rhythm. The conversion will help make genomic coding sequences more approachable for the general public, young children, and vision-impaired scientists.
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收藏
页数:4
相关论文
共 13 条
[1]   Embezzlement scandal rocks Korean universities [J].
Cyranoski, D .
NATURE, 2005, 436 (7054) :1072-1072
[2]   Life music: The sonification of proteins [J].
Dunn, J ;
Clark, MA .
LEONARDO, 1999, 32 (01) :25-32
[3]  
Gena P., 2001, CADE 2001, P129
[4]  
Gena P, 1995, 11 C INF MUS NOV 199, P203
[5]  
HANCE BD, 1996, ARIZONA DAILY W 0131
[6]   Synesthesia-like mappings of lightness, pitch, and melodic interval [J].
Hubbard, TL .
AMERICAN JOURNAL OF PSYCHOLOGY, 1996, 109 (02) :219-238
[7]  
Ione Amy, 2004, J Hist Neurosci, V13, P58, DOI 10.1080/09647040490885493
[8]   AUDITORY-VISUAL SYNESTHESIA - SOUND-INDUCED PHOTISMS [J].
JACOBS, L ;
KARPIK, A ;
BOZIAN, D ;
GOTHGEN, S .
ARCHIVES OF NEUROLOGY, 1981, 38 (04) :211-216
[9]  
Jensen E., 2001, MATH J, V8, P55
[10]   A NOVEL GENE CONTAINING A TRINUCLEOTIDE REPEAT THAT IS EXPANDED AND UNSTABLE ON HUNTINGTONS-DISEASE CHROMOSOMES [J].
MACDONALD, ME ;
AMBROSE, CM ;
DUYAO, MP ;
MYERS, RH ;
LIN, C ;
SRINIDHI, L ;
BARNES, G ;
TAYLOR, SA ;
JAMES, M ;
GROOT, N ;
MACFARLANE, H ;
JENKINS, B ;
ANDERSON, MA ;
WEXLER, NS ;
GUSELLA, JF ;
BATES, GP ;
BAXENDALE, S ;
HUMMERICH, H ;
KIRBY, S ;
NORTH, M ;
YOUNGMAN, S ;
MOTT, R ;
ZEHETNER, G ;
SEDLACEK, Z ;
POUSTKA, A ;
FRISCHAUF, AM ;
LEHRACH, H ;
BUCKLER, AJ ;
CHURCH, D ;
DOUCETTESTAMM, L ;
ODONOVAN, MC ;
RIBARAMIREZ, L ;
SHAH, M ;
STANTON, VP ;
STROBEL, SA ;
DRATHS, KM ;
WALES, JL ;
DERVAN, P ;
HOUSMAN, DE ;
ALTHERR, M ;
SHIANG, R ;
THOMPSON, L ;
FIELDER, T ;
WASMUTH, JJ ;
TAGLE, D ;
VALDES, J ;
ELMER, L ;
ALLARD, M ;
CASTILLA, L ;
SWAROOP, M .
CELL, 1993, 72 (06) :971-983