Non-criteria manifestations of antiphospholipid syndrome

被引：50

作者：

Erkan, D. ^{[1
]}

Lockshin, M. D. ^{[1
]}

机构：

[1] Cornell Univ, Hosp Special Surg, Weill Med Coll, Barbara Volcker Ctr Women & Rheumat Dis, New York, NY 10021 USA

来源：

LUPUS | 2010年 / 19卷 / 04期

关键词：

antiphospholipid syndrome; antiphospholipid nephropathy; cardiac valve disease; cognitive dysfunction; skin ulcers; thrombocytopenia; ANTIBODY SYNDROME; COGNITIVE DEFICITS; INVOLVEMENT; THROMBOCYTOPENIA; MICROANGIOPATHY; ASPIRIN; HEPARIN;

D O I：

10.1177/0961203309360545

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Only few studies have addressed the pathogenesis and treatment of the non-criteria manifestations of antiphospholipid antibodies (aPL) such as thrombocytopenia, nephropathy, cardiac valve disease, cognitive dysfunction, skin ulcers, or diffuse pulmonary hemorrhage. There is no consensus on the management of these manifestations; they may occur despite full-dose anticoagulation or may not improve if anticoagulation is initiated after their discovery. This brief review may help physicians in the management of the non-criteria manifestations of aPL. Lupus (2010) 19, 424-427.

引用

页码：424 / 427

页数：4

共 32 条

[1] CTLA4Ig prevents initiation but not evolution of anti-phospholipid syndrome in NZW/BXSB mice [J].