The hair follicle enigma

被引：30

作者：

Bernard, Bruno A. ^{[1
]}

机构：

[1] LOreal Res & Innovat, Asnieres, France

来源：

EXPERIMENTAL DERMATOLOGY | 2017年 / 26卷 / 06期

关键词：

hair follicle; perspectives; GENOME-WIDE ASSOCIATION; DERMAL PAPILLA CELLS; OUTER ROOT SHEATH; ANDROGENETIC ALOPECIA; HEPARAN-SULFATE; SUSCEPTIBILITY LOCI; KERATIN NETWORK; ANAGEN PHASE; STEM-CELLS; IN-VITRO;

D O I：

10.1111/exd.13337

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The hair follicle is a mini-organ endowed with a unique structure and cyclic behaviour. Despite the intense research efforts which have been devoted at deciphering the hair follicle biology over the past 70years, one must admit that hair follicle remains an enigma. In this brief review, various aspects of hair follicle biology will be addressed, and more importantly, unsolved questions and new possible research tracks will be highlighted, including hair follicle glycobiology and exosome-mediated cell-cell interactions. Even though bricks of knowledge are solidly being acquired, an integrative picture remains to emerge. One can predict that computer science, algorithms and bioinformatics will assist in fostering our understanding hair biology.

引用

页码：472 / 477

页数：6

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