Chemoselective C-S/S-S Formation between Diaryl Disulfides and Tetraalkylthiuram Disulfides

被引：33

作者：

Peng, Kang ^{[1
]}

Zhu, Hui ^{[1
]}

Liu, Xing ^{[1
]}

Peng, Han-Ying ^{[1
]}

Chen, Jin-Quan ^{[1
]}

Dong, Zhi-Bing ^{[1
,2
,3
]}

机构：

[1] Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430205, Hubei, Peoples R China

[2] Wuhan Inst Technol, Key Lab Green Chem Proc, Minist Educ, Wuhan 430205, Hubei, Peoples R China

[3] Hubei Univ, Minist Of Educ, Key Lab Synth & Applicat Organ Funct Mol, Wuhan 430062, Hubei, Peoples R China

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 2019卷 / 47期

基金：

中国国家自然科学基金;

关键词：

Dithiocarbamates; Tetraalkylthiuram disulfide; Synthesis design; Chemoselectivity; C-S; S-S formation; COPPER-CATALYZED SYNTHESIS; POTENT INHIBITORS; ARYL IODIDES; DITHIOCARBAMATE; DERIVATIVES; 2-AMINOBENZOTHIAZOLES; ARYLTHIOINDOLES; APOPTOSIS; WATER;

D O I：

10.1002/ejoc.201901401

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient C-S/S-S formation for the chemoselective synthesis of aryl dithiocarbamate (C-S formation) and aryl dialkylcarbamo(dithioperoxo)thioate (S-S formation) was studied. The chemoselectivity could be controlled by modulating the reaction temperature, base, and catalyst. The transformation features a simple reaction, easily available starting materials, high selectivity and easy performance, showing its practical synthetic value for the preparation of some potential biologically or pharmaceutically active compounds.

引用

页码：7629 / 7634

页数：6

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