Synthesis of 4-aryl-2-thioxo-3,4-dihydropyrimidines using a three-component reaction of Meldrum's acid with arylaldehydes and acetylthiourea

被引：2
|
作者：
Mehrabi, Hossein
Yarahmadi, Tayebeh
Bami, Farzaneh Alizadeh
机构：
[1] Department of Chemistry, Vali-e-Asr University of Rafsanjan, Rafsanjan
来源：
JOURNAL OF CHEMICAL RESEARCH | 2018年 / 06期
关键词：
Meldrum's acid; arylaldehydes; acetylthiourea; p-toluenesulfonic acid; 4-aryl-2-thioxo-3,4-dihydropyrimidincs; ONE-POT SYNTHESIS; SOLVENT-FREE CONDITIONS; BIGINELLI REACTION; REUSABLE CATALYST; BIOLOGICAL EVALUATION; LEWIS-ACID; 3,4-DIHYDROPYRIMIDIN-2(1H)-ONES; DERIVATIVES; EFFICIENT; DIHYDROPYRIMIDINONES;
D O I：
10.3184/174751918X15293155829494
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A one-pot method for the preparation of new 4-aryl-2-thioxo-3,4-dihydropyrimidines via a three-component reaction of Meldrum's acid with arylaldehydes and acetylthiourea in the presence of p-toluenesulfonic acid as catalyst in CH3CN under reflux is reported.
引用
收藏
页码：326 / 328
页数：3
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