2-amino-6-(1,2,4-triazol-4-yl)-purine: a useful intermediate in the synthesis of 9-alkylguanines

被引：7

作者：

Alarcon, K ^{[1
]}

Martelli, A ^{[1
]}

Demeunynck, M ^{[1
]}

Lhomme, J ^{[1
]}

机构：

[1] Univ Grenoble 1, CNRS, UMR 5616, LEDSS, F-38041 Grenoble 9, France

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 37期

关键词：

guanine; 2,6-diaminopurine; 1,2,4-triazole;

D O I：

10.1016/S0040-4039(00)01236-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Amino-6-(1,2,4-triazol-4-yl)purine, prepared from 2,6-diaminopurine, was regioselectively alkylated at position 9. Subsequent alkaline hydrolysis afforded 9-alkylguanines in high yield. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：7211 / 7215

页数：5

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