MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines

被引:616
作者
Filippi, Massimo [1 ]
Rocca, Maria A. [1 ]
Ciccarelli, Olga [2 ,3 ]
De Stefano, Nicola [4 ]
Evangelou, Nikos [5 ]
Kappos, Ludwig [6 ]
Rovira, Alex [7 ]
Sastre-Garriga, Jaume [8 ]
Tintore, Mar [8 ]
Frederiksen, Jette L. [9 ,10 ]
Gasperini, Claudio [11 ]
Palace, Jacqueline [12 ]
Reich, Daniel S. [13 ]
Banwell, Brenda [14 ]
Montalban, Xavier [8 ]
Barkhof, Frederik [15 ]
机构
[1] Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Div Neurosci, Neuroimaging Res Unit,Inst Expt Neurol, Milan, Italy
[2] UCL Inst Neurol, Dept Neuroinflammat, Queen Sq MS Ctr, London, England
[3] UCL UCLH Biomed Res Ctr, NIHR, London, England
[4] Univ Siena, Dept Med Surg & Neurosci, Via Laterina 8, I-53100 Siena, Italy
[5] Univ Nottingham, Div Neurosci, Queens Med Ctr Campus, Nottingham NG7 2RD, England
[6] Univ Basel, Dept Neurol, Basel, Switzerland
[7] Univ Autonoma Barcelona, Hosp Univ Vail dHebron, Dept Radiol IDI, Magnet Resonance Unit, E-08193 Barcelona, Spain
[8] Univ Autonoma Barcelona, Hosp Univ Vail dHebron, Dept Neurol Neuroimmunol, Ctr Esclerosi Multiple Catalunya Cemcat, E-08193 Barcelona, Spain
[9] Glostrup Cty Hosp, Dept Neurol, Copenhagen, Denmark
[10] Univ Copenhagen, Copenhagen, Denmark
[11] San Camillo Forlanini Hosp, Dept Neurosci, Rome, Italy
[12] Univ Oxford Hosp Trust, Dept Clin Neurol, Oxford, England
[13] NINDS, Translat Neuroradiol Unit, NIH, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA
[14] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Div Child Neurol,Dept Neurol, Philadelphia, PA 19104 USA
[15] Vrije Univ Amsterdam Med Ctr, MS Ctr Amsterdam, Amsterdam, Netherlands
基金
新加坡国家研究基金会;
关键词
2010 MCDONALD CRITERIA; CLINICALLY ISOLATED SYNDROMES; SENSITIVE INVERSION-RECOVERY; HIGH-FIELD MRI; SPINAL-CORD; CORTICAL-LESIONS; MS LESIONS; OPTIC NEURITIS; INTRACORTICAL LESIONS; PROPOSED MODIFICATION;
D O I
10.1016/S1474-4422(15)00393-2
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In patients presenting with a clinically isolated syndrome, MRI can support and substitute clinical information in the diagnosis of multiple sclerosis by showing disease dissemination in space and time and by helping to exclude disorders that can mimic multiple sclerosis. MRI criteria were first included in the diagnostic work-up for multiple sclerosis in 2001, and since then several modifications to the criteria have been proposed in an attempt to simplify lesion-count models for showing disease dissemination in space, change the timing of MRI scanning to show dissemination in time, and increase the value of spinal cord imaging. Since the last update of these criteria, new data on the use of MRI to establish dissemination in space and time have become available, and MRI technology has, improved. State-of-the-art MRI findings in these patients were discussed in a MAGNIMS workshop, the goal of which was to provide an evidence based and expert-opinion consensus on proposed modifications to MRI criteria for the diagnosis of multiple sclerosis.
引用
收藏
页码:292 / 303
页数:12
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