DYRK1A: A promising protein kinase target for cardiomyocyte cycling and cardiac repair through epigenetic modifications

被引:1
|
作者
Bei, Yihua [1 ,2 ]
Wang, Hongbao [3 ]
Xiao, Junjie [1 ,2 ]
机构
[1] Shanghai Univ, Sch Med, Cardiac Regenerat & Ageing Lab, Inst Geriatr,Nantong Hosp,Peoples Hosp Nantong 6, Nantong 226011, Peoples R China
[2] Shanghai Univ, Inst Cardiovasc Sci, Shanghai Engn Res Ctr Organ Repair, Sch Life Sci, Shanghai 200444, Peoples R China
[3] Tongji Univ, Yangpu Hosp, Dept Cardiol, Sch Med, Shanghai 200065, Peoples R China
来源
EBIOMEDICINE | 2022年 / 82卷
基金
中国国家自然科学基金; 上海市自然科学基金;
关键词
D O I
10.1016/j.ebiom.2022.104168
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Dyrk1a kinase controls cardiomyocyte proliferation
    Rizzari, Giorgia
    Dirkx, Ellen
    Torrini, Consuelo
    Tomczyk, Mateusz
    Mano, Miguel
    Giacca, Mauro
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022, 173 : S109 - S109
  • [2] Inhibition of DYRK1a Enhances Cardiomyocyte Cycling After Myocardial Infarction
    Young, Alexander
    Bradley, Leigh A.
    Farrar, Elizabeth
    Bilcheck, Helen O.
    Tkachenko, Svyatoslav
    Saucerman, Jeffrey J.
    Bekiranov, Stefan
    Wolf, Matthew J.
    CIRCULATION RESEARCH, 2022, 130 (09) : 1345 - 1361
  • [3] Elucidating The Role Of Dyrk1a Kinase In Controlling Cardiomyocyte Proliferation
    Rizzari, Giorgia
    Dirkx, Ellen
    Torrini, Consuelo
    Tomczyk, Mateusz
    Mano, Miguel
    Giacca, Mauro
    CIRCULATION RESEARCH, 2022, 131
  • [4] DYRK1A Protein, A Promising Therapeutic Target to Improve Cognitive Deficits in Down Syndrome
    Feki, Anis
    Hibaoui, Youssef
    BRAIN SCIENCES, 2018, 8 (10):
  • [5] DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly
    Litovchick, Larisa
    Florens, Laurence A.
    Swanson, Selene K.
    Washburn, Michael P.
    DeCaprio, James A.
    GENES & DEVELOPMENT, 2011, 25 (08) : 801 - 813
  • [6] Mutational analysis of two residues in the DYRK homology box of the protein kinase DYRK1A
    Widowati E.W.
    Bamberg-Lemper S.
    Becker W.
    BMC Research Notes, 11 (1)
  • [7] Specificity determinants of substrate recognition by the protein kinase DYRK1A
    Himpel, S
    Tegge, W
    Frank, R
    Leder, S
    Joost, HG
    Becker, W
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (04) : 2431 - 2438
  • [8] The MNB/DYRK1A protein kinase: genetic and biochemical properties
    Galceran, J
    de Graaf, K
    Tejedor, FJ
    Becker, W
    JOURNAL OF NEURAL TRANSMISSION-SUPPLEMENT, 2003, (67): : 139 - 148
  • [9] Effect of hyperhomocysteinemia on the protein kinase DYRK1A in liver of mice
    Hamelet, Julien
    Noll, Christophe
    Ripoll, Clementine
    Paul, Jean-Louis
    Janel, Nathalie
    Delabar, Jean-Maurice
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 378 (03) : 673 - 677
  • [10] Targeted degradation of the protein kinase DYRK1A using PROTACs
    Wilms, G.
    Schofield, K.
    Hulme, C.
    Becker, W.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2023, 396 : S24 - S24