Chronic-intermittent hypoxia induces immediate early gene expression in the midline thalamus and epithalamus

被引：33
|
作者：
Sica, AL
Greenberg, HE
Scharf, SM
Ruggiero, DA
机构：
[1] Albert Einstein Coll Med, Long Isl Jewish Med Ctr, Dept Med, Div Pulm & Crit Care, New York, NY 11040 USA
[2] Columbia Univ Coll Phys & Surg, Dept Psychiat, New York, NY 10032 USA
[3] Columbia Univ Coll Phys & Surg, Dept Anat & Cell Biol, New York, NY 10032 USA
[4] Neurol Res Inst Lubec, Lebec, ME 04652 USA
来源：
BRAIN RESEARCH | 2000年 / 883卷 / 02期
基金：
美国国家卫生研究院;
关键词：
chronic-intermittent hypoxia; rat; c-fos; paraventricular thalamic nucleus; habenular nucleus;
D O I：
10.1016/S0006-8993(00)02800-6
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Chronic-intermittent hypoxia (CIH) was postulated to activate thalamic regions that are synaptically related to autonomic-related areas of the cerebral cortex. Animals exposed to CIH for 30 days exhibited c-fos labeling in paraventricular thalamic and lateral habenular nuclei. Our findings strongly suggest activation of a diencephalic network that participates in behavioral responses to chronic stress. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：224 / 228
页数：5
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