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The Influence of Host miRNA Binding to RNA Within RNA Viruses on Virus Multiplication
被引:16
作者:
Lei, Lin
Cheng, Anchun
Wang, Mingshu
Jia, Renyong
机构:
[1] Research Center of Avian Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu
[2] Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu
[3] Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu
基金:
中国国家自然科学基金;
关键词:
miRNA;
RNA virus;
RISC complex;
argonaute2;
flavivirus;
HEPATITIS-C VIRUS;
MESSENGER-RNA;
MAMMALIAN MICRORNAS;
CELLULAR MICRORNAS;
VIRAL GENOME;
B-VIRUS;
GENE;
REPLICATION;
ARGONAUTE;
PROTEINS;
D O I:
10.3389/fcimb.2022.802149
中图分类号:
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号:
100102 ;
摘要:
microRNAs (miRNAs), non-coding RNAs about 22 nt long, regulate the post-transcription expression of genes to influence many cellular processes. The expression of host miRNAs is affected by virus invasion, which also affects virus replication. Increasing evidence has demonstrated that miRNA influences RNA virus multiplication by binding directly to the RNA virus genome. Here, the knowledge relating to miRNAs' relationships between host miRNAs and RNA viruses are discussed.
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页数:10
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