Preparation of vinyl ethers using a Wittig approach, and their subsequent hydrogenation employing continuous-flow processing

被引：12

作者：

Balti, Monaem ^{[1
]}

Efrit, Mohamed Lotfi ^{[1
]}

Leadbeater, Nicholas E. ^{[2
]}

机构：

[1] Univ El Manar, Lab Organ Synth & Heterocycl Chem, Fac Sci Tunis, Dept Chem, Tunis, Tunisia

[2] Univ Connecticut, Dept Chem, 55 North Eagleville Rd, Storrs, CT 06269 USA

来源：

TETRAHEDRON LETTERS | 2016年 / 57卷 / 16期

关键词：

Wittig reaction; Vinyl ether; Enol ethers; Hydrogenation; Flow chemistry; NAZAROV CYCLIZATION; ALCOHOLS; OLEFINATION; LACTONES; CATALYST; ACCESS; CORE;

D O I：

10.1016/j.tetlet.2016.03.037

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A methodology is reported for the preparation of various aromatic-functionalized vinyl ethers using a Wittig approach. The subsequent hydrogenation of the vinyl ether products to their saturated analogs is also performed and is streamlined by employing continuous-flow processing. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：1804 / 1806

页数：3

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