Dementia incidence declined in African-Americans but not in Yoruba

被引：57

作者：

Gao, Sujuan ^{[1
]}

Ogunniyi, Adesola ^{[2
]}

Hall, Kathleen S. ^{[3
]}

Baiyewu, Olusegun ^{[4
]}

Unverzagt, Frederick W. ^{[3
]}

Lane, Kathleen A. ^{[1
]}

Murrell, Jill R. ^{[5
]}

Gureje, Oye ^{[4
]}

Hake, Ann M. ^{[6
]}

Hendrie, Hugh C. ^{[3
,7
,8
]}

机构：

[1] Indiana Univ Sch Med, Dept Biostat, Indianapolis, IN 46202 USA

[2] Univ Ibadan, Coll Med, Dept Med, Ibadan, Nigeria

[3] Indiana Univ Sch Med, Dept Psychiat, Indianapolis, IN 46202 USA

[4] Univ Ibadan, Coll Med, Dept Psychiat, Ibadan, Nigeria

[5] Indiana Univ Sch Med, Dept Pathol & Lab Med, Indianapolis, IN 46202 USA

[6] Indiana Univ Sch Med, Dept Neurol, Indianapolis, IN 46202 USA

[7] Indiana Univ, Ctr Aging Res, Indianapolis, IN 46204 USA

[8] Regenstrief Inst Inc, Indianapolis, IN USA

来源：

ALZHEIMERS & DEMENTIA | 2016年 / 12卷 / 03期

关键词：

Dementia; Alzheimer's disease; Incidence; African-Americans; Nigerians; ALZHEIMERS-DISEASE; COGNITIVE IMPAIRMENT; UNITED-STATES; STANDARDIZED INSTRUMENT; MENTAL DISORDER; COMMUNITIES; PREVALENCE; TRENDS; POPULATION; DIAGNOSIS;

D O I：

10.1016/j.jalz.2015.06.1894

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction: To compare dementia incidence of African-American and Yoruba cohorts aged >= 70 years enrolled in 1992 and 2001. Methods: African-Americans residing in Indianapolis and Yoruba in Ibadan, Nigeria without dementia were enrolled in 1992 and 2001 and evaluated every 2-3 years until 2009. The cohorts consist of 1440 African-Americans, 1774 Yoruba in 1992 and 1835 African-Americans and 1895 Yoruba in the 2001 cohorts aged >= 70 years. Results: In African-Americans, dementia and Alzheimer's disease (AD) incidence rates were significantly lower in 2001 than 1992 for all age groups except the oldest group. The overall standardized annual dementia incidence rates were 3.6% (95% confidence interval [CI], 3.2%-4.1%) in the 1992 cohort and 1.4% (95% CI, 1.2%-1.7%) in the 2001 cohort. There was no significant difference in dementia or AD incidence between the Yoruba cohorts. Discussion: Future research is needed to explore the reasons for the differential changes in incidence rates in these two populations. (C) 2016 The Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

引用

页码：244 / 251

页数：8

共 29 条

[1]

[Anonymous], 1992, HLTH CAR US EXP PERS

[2]

[Anonymous], 1992, INT CLASS DIS

[3]

[Anonymous], 1987, DIAGNOSTIC STAT MANU, V4th

[4] POPULATION PREVALENCE ESTIMATES FROM COMPLEX SAMPLES [J].

BECKETT, LA ;

SCHERR, PA ;

EVANS, DA .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 1992, 45 (04) :393-402

[5] PREVALENCE OF ALZHEIMERS-DISEASE IN A COMMUNITY POPULATION OF OLDER PERSONS - HIGHER THAN PREVIOUSLY REPORTED [J].

EVANS, DA ;

FUNKENSTEIN, H ;

ALBERT, MS ;

SCHERR, PA ;

COOK, NR ;

CHOWN, MJ ;

HEBERT, LE ;

HENNEKENS, CH ;

TAYLOR, JO .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1989, 262 (18) :2551-2556

[6] Incidence and prevalence of dementia in the cardiovascular health study [J].

Fitzpatrick, AL ;

Kuller, LH ;

Ives, DG ;

Lopez, OL ;

Jagust, W ;

Breitner, JCS ;

Jones, B ;

Lyketsos, C ;

Dulberg, C .

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2004, 52 (02) :195-204

[7] Prevalence rates for dementia and Alzheimer's disease in African Americans: 1992 versus 2001 [J].

Hall, Kathleen S. ;

Gao, Sujuan ;

Baiyewu, Olusegun ;

Lane, Kathleen A. ;

Gureje, Oye ;

Shen, Jianzhao ;

Ogunniyi, Adesola ;

Murrell, Jill R. ;

Unverzagt, Frederick W. ;

Dickens, Jeanne ;

Smith-Gamble, Valerie ;

Hendrie, Hugh C. .

ALZHEIMERS & DEMENTIA, 2009, 5 (03) :227-233

[8]

Hall KS, 2000, INT J GERIATR PSYCH, V15, P521, DOI 10.1002/1099-1166(200006)15:6<521::AID-GPS182>3.0.CO

[9]

2-F

[10]

Hall KS, 1996, INT J METHOD PSYCH, V6, P129, DOI 10.1002/(SICI)1234-988X(199610)6:3<129::AID-MPR164>3.3.CO

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